Results 231 to 240 of about 253,120 (262)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Targeting the BMX in cancer: molecular mechanisms and emerging therapeutic strategies. [PDF]

J Enzyme Inhib Med Chem
Zhang M, Chen J, Liang R, Jiang W, Lin M, Wen S, Liu D, Yi B, Chen R, Chen T, Li Z.   +10 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

GABA-Producing Bacteria as Potential Psychobiotics in Gut-Brain Axis Regulation. [PDF]

Int J Mol Sci
Zielińska E, Kycia K, Mikołajczuk-Szczyrba A, Piłka N, Juszczuk-Kubiak E.   +4 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Phosphotyrosine proteomics reveals novel Zap70 and Itk pathway targets downstream of TCR and CAR in Jurkat T cells. [PDF]

Sci Rep
Callahan A, Trychanh SS, Ro T, Mojumdar A, Salomon AR.   +4 more
europepmc   +1 more source

Classical Phytohormones and Peptide Plant Hormones in Abiotic Stress Tolerance: Crosstalk, Physiological Integration, and Crop Improvement. [PDF]

Plants (Basel)
Ali B, Imran A, Iftikhar H, Khan Z, Saeed F, Hussain Z, Waheed A, Abdel Latef AAH, Imin N.   +8 more
europepmc   +1 more source

Diet, Metabolism and Synaptic Function: Integrating Evidence Across Models in Neurodegeneration Research. [PDF]

Biomedicines
Targett IL, Hancock JT, Craig TJ.
europepmc   +1 more source

Mechanistic Insights into Dihydromyricetin: Redox Modulation and Kinase-Mediated Control of Disease Pathogenesis. [PDF]

Int J Mol Sci
Fabiyi OA, Ogundele AV, Ibrahim SO, Ibrahim H, Silva HH.   +4 more
europepmc   +1 more source

Role of the WNT signalling pathway in physiological and pathological blood-brain barrier. [PDF]

Ann Med
Yang F, Wang F, Jiang Y, Qian D, Chen L.
europepmc   +1 more source