Results 151 to 160 of about 51,319 (296)

Device-Based Therapies for Refractory Angina. [PDF]

J Clin Med
Caffè A, Montone RA.
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

How I do it: sequential robot-assisted stereotactic biopsy and laser interstitial thermal therapy for epilepsy associated with brain tumors. [PDF]

Acta Neurochir (Wien)
Aboubakr O, Mathon B.
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Research on intelligent assembly method of aero-engine deep-cavity nuts based on torque-angle control. [PDF]

Sci Rep
Liu Z, Huang X, Tan J.
europepmc   +1 more source

Reducing cholesterol does not reduce mortality

Journal of the American College of Cardiology, 1988
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Synthesis and Performance Evaluation of a High-Temperature Salt-Resistant Fluid Loss Additive. [PDF]

ACS Omega
Ding Y, Wu X, Ma C, Yang C, Zhang J.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Coronary Sinus Reducer Implantation in a Patient With Cardiac Resynchronization Therapy and Defibrillator. [PDF]

JACC Case Rep
Di Lorenzo D, Falato S, Terracciano F, Granata F, Maresca G.   +4 more
europepmc   +1 more source