Results 71 to 80 of about 4,904 (198)

Advanced metal-support interactions in Cu/ZnO catalysts: the role of MOFs and ZrO₂ for enhanced methanol production. [PDF]

Nanoscale Adv
Pourmand M, Haghtalab A, Safari Yazd M.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Impact of Sm³⁺ Ions on Oxygen Vacancy Formation in Ceria Systems. [PDF]

Molecules
Keyhanian M, Koleva IZ, Aleksandrov HA.
europepmc   +1 more source

Solovay reducibility implies S2a-reducibility

The original notion of Solovay reducibility was introduced by Robert M. Solovay (unpublished notes) in 1975 as a measure of relative randomness. The S2a-reducibility introduced by Xizhong Zheng and Robert Rettinger (DOI:10.1007/978-3-540-27798-9_39) in 2004 is a modification of Solovay reducibility suitable for computably approximable (c.a.) reals ...
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Pt/Al₂O₃ Overcoated with Reactive Metal Oxides and Their Application to Catalytic Oxidation of Propane. [PDF]

Small Methods
Han GH, Koo K, Alayoglu S, W Brown S, M Notestein J.   +4 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Effect of MgO on the catalytic activity and stability of nickel-based catalyst in methane dry reforming reaction. [PDF]

Sci Rep
Sattari O, Nematollahi B, Rezaei M, Alavi SM.   +3 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

N₂O Formation Mechanism and Suppression Strategy on Pt Catalysts for NO _<i>x</i> Removal from Hydrogen-Internal Combustion Engines. [PDF]

JACS Au
Xie S, Li Y, Ye K, Ma L, Ehrlich SN, Liu F.   +5 more
europepmc   +1 more source