Results 181 to 190 of about 502,571 (335)

Identification of gut bacteria reductases that biotransform steroid hormones. [PDF]

Nat Commun
Arp G, Jiang AK, Dufault-Thompson K, Levy S, Zhong A, Wassan JT, Grant MR, Li Y, Hall B, Jiang X.   +9 more
europepmc   +1 more source

Isolation and Properties of Lens Aldose Reductase

, 1965
Selma Hayman, Jin H. Kinoshita
openalex   +1 more source

Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol

Angewandte Chemie, EarlyView.
A highly stereoselective, dynamic reductive kinetic resolution (DYRKR) entry into myriad Taxotere‐like side chains with Clostridium acetobutylicum alcohol dehydrogenase (CaADH) enzyme is reported. Follow‐on cross couplings expand the structural diversity of the library (36 total examples).
Gaurav P. Kudalkar, Florian Leidner, Nivesh Kumar, Jared L. Hass, Peter Madzelan, Douglas R. Powell, Victor W. Day, Pierre Le Magueres, Joseph D. Ferrara, Lee M. Daniels, Akihito Yamano, Sho Ito, Wei Niu, Helmut Grubmüller, Mark A. Wilson, David B. Berkowitz   +15 more
wiley   +2 more sources

Nitrate-Nitrite Interplay in the Nitrogen Biocycle. [PDF]

Molecules
Maiti BK, Moura I, Moura JJG.
europepmc   +1 more source

Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies

Oncogene, 2014
Y. Aye, Minxing Li, M. Long, Robert S. Weiss   +3 more
semanticscholar   +1 more source

The Iron–Sulfur Cluster of Bacterioferritin‐Associated Ferredoxin (Bfd): a “Biological Fuse” that Prevents Oxidative Damage to Cells?

Angewandte Chemie, EarlyView.
When cellular iron is low, bacterioferritin (Bfr) releases its stored iron through a reductive process dependent on the [2Fe–2S] ferredoxin Bfd. Why accessing stored iron should depend on an iron‐requiring protein when iron is scarce is unclear. Here, we show that the Bfd [2Fe–2S] cluster is sensitive to oxidative stress, suggesting that it may act as ...
Justin M. Bradley, Aiden M. Carter, Zinnia Bugg, Simon C. Andrews, Nick E. Le Brun   +4 more
wiley   +2 more sources

Deciphering chromate tolerance and reduction ability of an indigenous Bacillus strain isolated from polluted pond sludge for chromium bioremediation. [PDF]

Sci Rep
Adhikary S, Saha BK, Roy V, Saha J, Pal A.   +4 more
europepmc   +1 more source

On the Reaction Mechanism of Yeast Glutathione Reductase

, 1965
Vincent Massey, Charles H. Williams
openalex   +1 more source

Metabolic Engineering of the 5‐Aminolevulinate Biosynthetic Pathway in E. coli Improves Efficiency of Hemoprotein‐Based Biocatalysis

Angewandte Chemie, EarlyView.
We have engineered the heme biosynthetic pathway in E. coli to develop an efficient cofactor supplementation system for hemoproteins. Through the incorporation of the heterogeneous C4 pathway, the engineered cells significantly increase the expression levels of active holohemoproteins and enhance the efficiency of whole‐cell and lysate‐based ...
Shunsuke Kato, Miteki Abe, Nobuyuki Okahashi, Shinya Ariyasu, Fumio Matsuda, Osami Shoji, Takashi Hayashi   +6 more
wiley   +2 more sources

Subtractive proteo-genomics and model-based druggability analyses prioritized nitrate reductase-A subunit-α as potential therapeutic target against MDR pneumonia; a homology-based approach. [PDF]

BMC Microbiol
Begum K, Aiman S, Khan A, Mumtaz MN, Ali F, Hussain SA, Khan S, Shaik MR.   +7 more
europepmc   +1 more source