Results 211 to 220 of about 679,415 (356)

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

Advanced Science, EarlyView.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song, Yu Wei, Peng Jia, Shan He, Qian Wang, Manman Xu, Hongzhi Liu, Pengtao Bao, Shanyue Guan, Xiaozhong Qu   +9 more
wiley   +1 more source

Fe(III)-dependent Nrf activity determines nitrate reduction partitioning in nitrate-reducing communities. [PDF]

mBio
Zhan J, Zhang L, Lai S, Guo J, Lin T, Liu G, Rensing C, Liu X, Zhou S.   +8 more
europepmc   +1 more source

A Two‐Stage Cascading Amplification Strategy Based on Zn2+‐Doped WOX Nanozymes for Ultrasensitive Lateral Flow Immunoassays of Clostridium Difficile Toxin B

Advanced Science, EarlyView.
Based on the modulation of active sites and electronic structure of substrate materials, along with a colorimetric two‐stage cascading enhancement strategy, an LFIA platform with highly efficient POD‐mimetic enzymes is developed, achieving highly sensitive detection of Clostridium difficile toxin B.
Junhua Su, Zhenzhen Liu, Renjie Xiong, Renlong zhu, Zijin Tong, Yufei Liu, Rui Xiao   +6 more
wiley   +1 more source

Regulation of sterol metabolism by gut microbiota and its relevance to disease. [PDF]

Gut Microbes
Huang C, Wu Q, Wang J, Cai J, Wang Z, You L, Zhu Z, Ding Y.   +7 more
europepmc   +1 more source

Nitrogen‐Boosted H2O2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

Advanced Science, EarlyView.
PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang, Yaojia Yang, Aoxue Wang, Chen Shen, Shenliang Tan, Changsheng Liu, Yuzheng Zhao, Xue Qu   +7 more
wiley   +1 more source

Amino acid metabolism of the thermophilic acetogen Thermacetogenium phaeum. [PDF]

PLoS One
Cai Y, Marquardt A, Schleheck D, Müller N.   +3 more
europepmc   +1 more source

Overcoming statin resistance in prostate cancer cells by targeting the 3-hydroxy-3-methylglutaryl-CoA-reductase

Andy Göbel, Sophie Pählig, Anja Motz, Dorit Breining, Sofia Traikov, Lorenz C. Hofbauer, Tilman D. Rachner   +6 more
openalex   +1 more source

Catalytic Mechanism of Mycobacterium tuberculosis Methionine Sulfoxide Reductase A [PDF]

Santiago Sastre, Bruno Manta, Jonathan A. Semelak, Darío A. Estrı́n, Madia Trujillo, Rafael Radí, Ari Zeida   +6 more
openalex   +1 more source

Methylenetetrahydrofolate Reductase C677T Distribution among Cervical Cancer Patients at Dr. Hasan Sadikin General Hospital [PDF]

, 2016
Ani Melani Maskoen, Cynthia Kurniawan, Edhyana Sahiratmadja, Herman Susanto   +3 more
openalex   +1 more source

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

Advanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng, Haoran Sun, Jin Cheng, Ruyi Zhao, Jianzhu Xie, Yanwei Song, Yucui Zhao, Chenwei Lin, Binjie Hu, Yanping Gong, Jun Lin, Sijia He, Yuntao Luo, Minghui Zhao, Yiwei Wang, Ming Jiao, Yuqin Yang, Jikun Li, Shujie Xia, Chuanyuan Li, Qian Huang   +20 more
wiley   +1 more source