Results 231 to 240 of about 521,718 (340)
Chemistry &Biodiversity, EarlyView.This graphical abstract represents the extraction, characterization, and biological evaluation of bioactive compounds derived from specific plant sources. The top section illustrates Rhus coriaria (sumac) fruit, Punica granatum (pomegranate) peel and Terminalia catappa (Indian almond) leaves', which are known for their rich phytochemical composition ...
Mudassir Nazir +8 more
wiley +1 more source
ChemBioChem, EarlyView.This study describes the successful identification of ancestral sequences N50 and N49, which have a longer half‐life of approximately four and two times the wild‐type Sp‐amine transaminase, respectively.. This approach effectively enhances the thermal stability of the transaminase.
Luyao Zhao +4 more
wiley +1 more source
The Occurrence of Nitrate Reductase in Apple Leaves
, 1969 Lowell Klepper, R. H. Hageman
openalex +1 more source
Clade III Synthases Add Cyclic and Linear Terpenoids to the Psilocybe Metabolome
ChemBioChem, EarlyView.The Psilocybe cubensis terpene synthases, CubB‐CubE, were investigated. Product formation assays identified CubB as a (3R,6E)‐(‐)‐nerolidol or linalool synthase, whereas CubC is a multiproduct synthase catalyzing the formation of β‐caryophyllene and other linear and cyclic sesquiterpenes/‐terpenoids.
Nick Zschoche +7 more
wiley +1 more source
PCFT‐Independent Cellular Uptake of Cyclic Cell‐Penetrating Peptide‐Conjugated Folic Acid
ChemBioChem, EarlyView.Cell‐penetrating peptide (CPP)‐conjugated folic acid mediates efficient internalization of folic acid that is independent of the presence of proton‐coupled folate transporter (PCFT) on the intestinal cells. CPP‐conjugated folic acid demonstrates superior cellular uptake at all studied pH and in the presence of PCFT inhibitors and shows enhanced ...
Vineet Kumar Mishra +3 more
wiley +1 more source
ChemBioChem, EarlyView.This study shows that the flavin‐dependent tryptophan halogenase Thal also regioselectively halogenates the tricyclic non‐native substrate tryptoline, a β‐carboline with various pharmacological activities. Interestingly, Thal brominates a different position of the shared pharmacophore indole in tryptoline than it does in tryptophan. A crystal structure
Simon Bork +3 more
wiley +1 more source
ChemBioChem, Accepted Article.Upon cell stimulation, mammalian cells activate various signaling proteins and lipids by recruiting their upstream regulators to the inner leaflet of the plasma membrane (PM), which in turn determines their cellular response. Therefore, artificially inducing protein translocation to the PM is an effective strategy for dissecting cell signaling networks
Shuya Ohira +3 more
wiley +1 more source