Results 231 to 240 of about 679,415 (356)

Aldose Reductase Inhibition by <i>Orthosiphon stamineus</i> Extracts and Constituents Suggests Antioxidant Potential. [PDF]

Molecules
Dawood Y, Zgair A, Yam MF, Abdul Aziz NHK.   +3 more
europepmc   +1 more source

Targeting Tuberculosis and Malaria through Inhibition of Enoyl Reductase [PDF]

, 2003
Mack Kuo, Héctor R. Morbidoni, David Alland, Scott Sneddon, Brian B. Gourlie, Mark M. Staveski, Marina Leonard, Jill S. Gregory, Andrew D. Janjigian, Christopher Yee, James M. Musser, Barry N. Kreiswirth, Hiroyuki Iwamoto, Remo Perozzo, William R. Jacobs, James C. Sacchettini, David A. Fidock   +16 more
openalex   +1 more source

Variants in AKR1D1 and Infant Mortality: Should Bile Acid Screening be a Routine Part of Newborn Screening?

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic pathogenic variants in AKR1D1 cause Δ4‐3‐oxosteroid 5β‐reductase deficiency, disrupt bile acid synthesis, and result in Congenital Bile Acid Synthesis defect type 2 (CBAS2). CBAS2 presents in infancy with cholestasis, coagulopathy, and failure to thrive.
Jade Hudson, Stephanie Hyunh, Bojana Rakic, Cornelius Boerkoel   +3 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

Angewandte Chemie, EarlyView.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet, Belén Pepió‐Tárrega, Javier Saiz‐Poseu, Alba López‐Moral, Faiz Ullah, Victor J. Yuste, Daniel Ruiz‐Molina, Salvio Suárez‐García   +7 more
wiley   +2 more sources

A Causal Association Between Drug Use and Cognitive Impairment: A Two-Sample Mendelian Randomization Study. [PDF]

Brain Behav
Yan B, Chen Z, Yang D.
europepmc   +1 more source

Biliverdin reductase-A is a key modulator in insulin signaling and metabolism [PDF]

Antonella Tramutola, Fabio Di Domenico, Marzia Perluigi, Eugenio Barone   +3 more
openalex   +1 more source

Pteridine reductase (PTR1); dihydrofolate reductase (DHFR) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

Animal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou, Huajun Wang, Hao Guo, Dongbin Luo, Xiaofei Zheng, Simin Luo   +5 more
wiley   +1 more source

Amide and Thioester Synthesis Via Oxidative Coupling of Alcohols with Amines or Thiols Using Alcohol Dehydrogenases

Angewandte Chemie, EarlyView.
Alcohol dehydrogenases (ADHs) are best known for reducing ketones to chiral alcohols, but their oxidative potential is rarely exploited. Here, we show that selected ADHs catalyze newly discovered promiscuous transformations: the oxidative coupling of primary alcohols with amines or thiols, enabling the direct and efficient synthesis of a broad range of
Matteo Damian, Vasilis Tseliou, Patrick Peters, Tanja Knaus, Francesco G. Mutti   +4 more
wiley   +2 more sources

Molecular Interaction of Genes Related to Anthocyanin, Lipid and Wax Biosynthesis in Apple Red-Fleshed Fruits. [PDF]

Int J Mol Sci
Keller-Przybyłkowicz SE, Oskiera M, Walencik A, Lewandowski M.   +3 more
europepmc   +1 more source