The roles of CymA in support of the respiratory flexibility of Shewanella oneidensisMR-1 [PDF]
Akagawamatsushita +41 more
core +1 more source
Adropin is related to the energy homeostasis‐associated gene. It significantly increased glutathione reductase enzyme levels in the pancreas of experimental diabetic rats. Adropin may reduce the severity of diabetes and its complications. Cell proliferation in the exocrine is reduced after the administration of adropin.
Ifrah I. Ali +4 more
wiley +1 more source
Some Like It Hot –Structural Changes in Extremophile Rubredoxin at 120 °C
We reveal the high temperature crystal structure of a hyperthermophilic (Pyrococcus furiosus) rubredoxin at 393 K (120 °C), together with multiple complementary structures down to 100 K. The results are compared with molecular dynamics calculations. Significant changes in H‐bonding are observed.
Tzanko Doukov +4 more
wiley +2 more sources
Multi-omics analysis reveals the mechanism of selenite reduction by <i>Rhodococcus qingshengii</i> strain isolated from selenium-rich mine. [PDF]
An J +5 more
europepmc +1 more source
Metabolism‐Regulating Nanomedicines for Cancer Therapy
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley +1 more source
Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler +4 more
wiley +2 more sources
The inoculation with Pseudomonas simiae WCS417 strain promotes growth and the induction of iron-deficiency responses in cucumber plants (Cucumis sativus L.). [PDF]
Aparicio MA +4 more
europepmc +1 more source
Analysis of the complete genome sequence of <i>Bradyrhizobium diazoefficiens</i> 172S4, a highly efficient nitrogen-fixing symbiont of soybeans, reveals large-scale genomic inversion. [PDF]
Bromfield ESP, Cloutier S.
europepmc +1 more source
Fluorescent probes derived from all three clinically used polyene antifungals (amphotericin B, nystatin, and natamycin) enabled direct visualization of distribution in yeast cells of various Candida species. While retaining the ergosterol‐dependent mode of action of their parent drugs, the probes revealed distinct, structure‐specific localization ...
Melissa Shbeta +6 more
wiley +2 more sources

