Results 251 to 260 of about 679,415 (356)

18F‐Radiopharmaceutical Diversification Enabled by Deaminative Cross‐Electrophile Couplings

Angewandte Chemie, EarlyView.
A general Ni‐mediated (C)sp2–(C)sp3 cross‐coupling expedites access to 18F‐radiopharmaceuticals, essential for positron emission tomography imaging and drug discovery. This late‐stage diversification approach was implemented across three user‐friendly automated protocols affording 18F‐radiotracers in sufficient quantities for imaging.
Isabella F. Ogilvy, Joseph Ford, Sebastiano Ortalli, Evelien Renders, Thomas R. Hayes, Shuanglong Liu, Inne Mortiers, Anastasia Nikolopoulou, Alexandre M. Sorlin, Andrés A. Trabanco, Matthew Tredwell, Peter J. J. A. Buijnsters, Rhys Salter, Véronique Gouverneur   +13 more
wiley   +2 more sources

Plumbagin Protects Diabetogenic Cataract Formation by Mitigating Lens Aldose Reductase and Oxidative Stress. [PDF]

J Pharmacopuncture
Yadav A, Choudhary R, Ram A, Nirmalkar U, Paul SD.   +4 more
europepmc   +1 more source

Infrared spectroscopy reveals metal-independent carbonic anhydrase activity in crotonyl-CoA carboxylase/reductase

Aharon Gómez, Matthias Tinzl, Gabriele Stoffel, Hendrik Westedt, Helmut Grubmüller, Tobias J. Erb, Esteban Vöhringer‐Martinez, Sven T. Stripp   +7 more
openalex   +2 more sources

Thiopurine S-Methyltransferase and Methylenetetrahydrofolate Reductase Polymorphisms in Leukemia

, 2015
Serhan Küpeli
openalex   +1 more source

Treatment of Single Patient With PMM2-Congenital Disorder of Glycosylation With Govorestat (AT-007), an Aldose Reductase Inhibitor. [PDF]

JIMD Rep
Jalazo ER, Weisenfeld LA, Ligezka A, Perfetti R, Muenzer J.   +4 more
europepmc   +1 more source

Hydrogen sulfide alleviates neural degeneration probably by reducing oxidative stress and aldose reductase expression

Wenqi Shen, Tingyu Hu, Xin Wang, Xiaoyan Zhang, Junxi Lu, Huijuan Lu, Yanyun Hu, Fang Liu   +7 more
openalex   +1 more source

Elucidating the drought-responsive changes in poplar cuticular waxes: a GWAS analysis of genes involved in fatty acid biosynthesis. [PDF]

Tree Physiol
Karaca-Bulut M, Gonzales-Vigil E, Muchero W, Mansfield SD.   +3 more
europepmc   +1 more source

NMR studies of singly cross-linked DNA duplexes and the trimethoprim-resistant dihydrofolate reductase mutant DHFR(F98Y)

, 1996
S. Altmann
openalex   +1 more source

Design of a Multienzyme Derived from Mouse Fatty Acid Synthase for the Compartmentalized Production of 2‐Pyrone Polyketides

Angewandte Chemie International Edition, EarlyView.
A multienzyme was formed and evaluated by covalently linking 4‐coumarate ligase (4CL1) from Piper methysticum to a non‐reducing murine fatty acid synthase. 4CL1 acylates the acyl carrier protein (ACP). The ketosynthase (KS) was engineered to accept the non‐native cinnamoyl substrate, which is elongated by malonyl‐CoA loaded via the malonyl‐acetyl ...
Felix Lehmann, Nadja Joachim, Carolin Parthun, Martin Grininger   +3 more
wiley   +1 more source

Expression of Concern: Ubiquitination and Degradation of Ribonucleotide Reductase M1 by the Polycomb Group Proteins RNF2 and Bmi1 and Cellular Response to Gemcitabine. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source