Results 261 to 270 of about 502,571 (335)

The Role and Regulation of Intramuscular Sex Hormones in Skeletal Muscle: A Systematic Review.

J Clin Endocrinol Metab
Engman V, Critchlow AJ, Laakkonen EK, Hansen M, Mason S, Lamon S.   +5 more
europepmc   +1 more source

Male and female pattern hair loss. [PDF]

Aust Prescr
Iyengar L, Li J.
europepmc   +1 more source

Development and Recent Advances in SLIPT‐PM: A Chemogenetic Platform for Manipulating Signaling at the Plasma Membrane

ChemBioChem, EarlyView.
SLIPT‐PM enables the translocation of tag‐fused proteins from the cytoplasm to the plasma membrane using a synthetic self‐localizing ligand. This user‐friendly system permits reversible control of diverse signaling pathways. This concept article highlights the key features and current applications of SLIPT‐PM as a powerful tool in chemical and ...
Shuya Ohira, Akinobu Nakamura, Kenta Terai, Shinya Tsukiji   +3 more
wiley   +1 more source

Physiological Stress Response to Sulfide Exposure of Freshwater Anaerobic Methanotrophic Archaea. [PDF]

Environ Sci Technol
Echeveste Medrano MJ, Lee S, de Graaf R, Holohan BC, Sánchez-Andrea I, Jetten MSM, Welte CU.   +6 more
europepmc   +1 more source

Gold‐Dithiocarbamato Glycoconjugates as Potential Anticancer Agents: Design, Physico‐Chemical Characterization and In Vitro Biological Activity

ChemBioChem, Accepted Article.
In order to develop new metal‐based glycoconjugates as potential anticancer agents, three gold(III)‐dithiocarbamato glycoconjugates of the type [AuIIIBr2(SSC‐Inp‐GlcN)] (Au3‐5), their gold(I)‐phosphine counterparts [AuI(SSC‐Inp‐GlcN)(PPh3)] (AuP3‐5) and gold(I)‐carbene analogues [AuI(SSC‐Inp‐GlcN)(Et2BzImy)] (AuC3‐5) (Inp: isonipecotic moiety; GlcN ...
Andrea Pettenuzzo, Jessica Wölker, Luciano Marchiò, Ingo Ott, Luca Ronconi   +4 more
wiley   +1 more source

Quantitative proteomic analysis deciphers mechanisms of sheath blight resistance in novel rice landrace against Rhizoctonia solani. [PDF]

Sci Rep
Mohanan A, Prashanthi SK, Arun YP, Raghunandana A, Krishnaraj PU, Nayak SN, Hegde Y.   +6 more
europepmc   +1 more source

Shifting the Substrate Scope of an Ene/Yne‐Reductase by Loop Engineering

ChemCatChem, EarlyView.
A flexible active‐site loop that is involved in shaping the substrate and product cleft as well as the active‐site pocket was identified for the MDR‐related ene/yne‐reductase CaeEnR1 from Cyclocybe aegerita. Double mutations of this loop showed an up to 20‐fold increase in conversion rates toward cinnamaldehyde‐like substrates and a 2‐fold increase in ...
Dominik Karrer, Erika Wedler, Carolin Mewe, Martin Gand, Marian Vogt, Lukas Korf, Lars‐Oliver Essen, Martin Rühl   +7 more
wiley   +1 more source

Role of oral and gut microbiomes in enterosalivary nitrate metabolism and their effects on systemic disease. [PDF]

Front Cell Infect Microbiol
Yang Z, Du C, Chang Z, Yang Y, Hu L.
europepmc   +1 more source

Rational Design of Hydrophilic Deep Eutectic Solvents to Outperform Oxidoreductase Activity in Aqueous Media

ChemCatChem, EarlyView.
This study investigates the catalytic performance of alcohol dehydrogenases (ADHs) — including thermostability, specific activity, and kinetics — in mixtures of glycerol‐based deep eutectic solvents (DESs) and aqueous buffers. By elucidating enzyme—DES interactions, the work identifies the outperforming hydrophilic DESs that enhance redox biocatalysis,
Ningning Zhang, Estelle Schwarz, Jan Philipp Bittner, Sven Jakobtorweihen, Irina Smirnova, Pablo Domínguez de María, Selin Kara   +6 more
wiley   +1 more source