Results 281 to 290 of about 521,718 (340)

Identification of hub genes for the diagnosis associated with heart failure using multiple cell death patterns

ESC Heart Failure, EarlyView.
Abstract Aims Heart failure (HF) is an important public health problem worldwide, and programmed cell death (PCD) plays a crucial role in its pathologic process. This study aims to identify the hub genes associated with HF through PCD in order to better understand the pathogenesis of HF and improve its diagnosis and treatment.
Hua‐jing Yuan, Hui Yu, Yi‐ding Yu, Xiu‐juan Liu, Wen‐wen Liu, Yi‐tao Xue, Yan Li   +6 more
wiley   +1 more source

Synthesis, characterization and antimicrobiological activity of copper(II) complexes containing ligands derived from azoles and coumarins

European Journal of Inorganic Chemistry, Accepted Article.
Four Cu(II) complexes with coumarin‐derived ligands were synthesized and fully characterized, confirming a ratio of 1:1 ligand to metal. The complex C3 presented a geometry between square pyramid and trigonal bipyramid with a supramolecular arrangement ruled by hydrogen bonding.
David Enrique Ezenarro Salcedo, Daniela Fonseca López, Sandra Leal Pinto, Martha V. Roa-Cordero, Jose D Vargas-Caicedo, Mario A Macías, Bernardo A Iglesias, Paulo C. Piquini, John Hurtado   +8 more
wiley   +1 more source

Isolation, Purification, and Some Properties of Reduced Nicotinamide Adenine Dinucleotide Phosphate-Cytochrome c2 Reductase from Rhodopseudomonas spheroides

, 1968
D. J. Sabo, Joseph A. Orlando
openalex   +1 more source

Expanding the Chemical Space of Allyl Palladates with Anticancer Properties

European Journal of Inorganic Chemistry, EarlyView.
Novel allyl palladates with diverse azolium ligands exhibit strong cytotoxicity against cancer cells, with some surpassing cisplatin. Compounds with thioether or selenoether groups show the best selectivity, making them promising candidates for further study. Allyl palladates are emerging as promising anticancer agents due to their unique mechanisms of
Alessia Schiavo, Giacomo Baio, Francis Bru, Irene Guerra, Victoria Mechrouk, Thierry Achard, Sara Baldissin, Stéphane Bellemin‐Laponnaz, Catherine S. J. Cazin, Cristina Tubaro, Fabiano Visentin, Isabella Caligiuri, Flavio Rizzolio, Steven P. Nolan, Thomas Scattolin   +14 more
wiley   +1 more source

Terpenes and Terpenoids: How can we use them?

European Journal of Organic Chemistry, EarlyView.
The transition from petroleum‐based to renewable bio‐based chemicals has led to increased interest in terpenes and terpenoids. This overview highlights their chemistry, focusing on their reactivity and applications in polymerizations, total syntheses, pharmaceuticals, and bio‐based chemical conversions; promoting sustainable and green chemical ...
Jay Hanssens, Diego Meneses, Jordy M. Saya, Romano V. A. Orru   +3 more
wiley   +1 more source

Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine

European Journal of Organic Chemistry, EarlyView.
Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng, Xavier Franck, Thibault Gallavardin   +2 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

NIR II‐Guided Photoactivatable Silencing Polyplex Boosts Cancer Immunotherapy

Exploration, EarlyView.
Due to limitation of penetration therapy with first and second‐generation photodynamic therapy (PDT) photosensitizers, an NIR II‐guided photoactivatable complex was proposed via the self‐assembly of the photosensitive polymer PTSQ and the electrostatic adsorption of siPD‐L1 to enhance cancer immunotherapy.
Yuquan Zhang, Jie Wang, Tian Zhang, Dongsheng Tang, Haiyin Yang, Shuai Guo, Yuchuan Fan, Caixia Sun, Haihua Xiao, Yuanyu Huang, Yuhua Weng   +10 more
wiley   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source

Application of Ferulic Acid to Alleviate Chilling Injury of Banana Fruit by Regulating Redox, Phenylpropanoid, and Energy Metabolism

Food Frontiers, EarlyView.
This study investigated the effect of ferulic acid (FA) on the cold tolerance of banana fruit under 6°C‐storage for 7 days. In comparison with control, 3 mM FA treatment significantly alleviated chilling symptoms of banana fruit by enhancing phenylpropanoid metabolism and maintaining redox and energy homeostasis. ABSTRACT Banana fruit is susceptible to
Yu Hou, Min Gou, Zhengke Zhang, Lanhuan Meng, Lisha Zhu, Xiangbin Xu, Taotao Li, Yueming Jiang, Jianbo Xiao, Jiali Yang   +9 more
wiley   +1 more source