Results 101 to 110 of about 948,522 (286)

Beam Wandering in the Atmosphere: The Effect of Partial Coherence

, 2007
The effect of a random phase screen on laser beam wander in a turbulent atmosphere is studied theoretically. The method of photon distribution function is used to describe the photon kinetics of both weak and strong turbulence.
A. A. Chumak, A. Belmonte, G. P. Berman, G. P. Berman, V. A. Banakh, V. N. Gorshkov   +5 more
core   +2 more sources

Interplay between Swelling Kinetics and Nanostructure in Perfluorosulfonic Acid Thin-Films: Role of Hygrothermal Aging [PDF]

, 2019
Impacts of processing, storage, and operation on thin-film perfluorosulfonic acid (PFSA) ionomer coatings used in electrodes of electrochemical devices remains unestablished.
Kushner, DI, Kusoglu, A, Tesfaye, M
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Mass-transport resistances of acid and alkaline ionomer layers: A microelectrode study part 1 - Microelectrode development [PDF]

, 2019
The use of microelectrodes to study localized mass-transport phenomena in fuel-cell catalyst layers is an increasingly valuable tool. However, existing microelectrode cells have been used in static, equilibrated environment modes with poorly controlled ...
Danilovic, N, Kushner, DI, Petrovick, JG, Radke, CJ, Tesfaye, M, Weber, AZ   +5 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Kinetics Calculation of the Non-isothermal Reduction of Pellet

High Temperature Materials and Processes, 2016
The reduction tests of pellet were carried out from room temperature to 1,373 K in the condition of traditional blast furnace (TBF) and oxygen blast furnace (OBF) by thermogravimeter measurement. The apparent activation energy E, pre-exponential factor A
Yingli Liu, Jingsong Wang, Wentao Guo, Zeshang Dong, Qingguo Xue   +4 more
doaj   +1 more source

Model Reduction in Kinetic Theory [PDF]

, 2006
Methods to derive macroscopic transport equations for rarefied gases from the Boltzmann equations are presented. Featured methods include the Chapman-Enskog expansion, Grad’s moment method, and the author’s order of magnitude method. The resulting macroscopic equations are compared and discussed by means of simple problems, including linear stability ...
openaire   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source