Results 51 to 60 of about 396,665 (316)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Effect of H₂–CO Ratio on Reduction Disintegration Behavior and Kinetics of Vanadium–Titanium Magnetite Pellets

Metals
There are many advantages of the smelting of vanadium–titanium magnetite pellets by hydrogen-based shaft furnace pre-reduction and electric arc furnace process, including high reduction efficiency, low carbon dioxide emission and high recovery of ...
Feng Chen, Hao Li, Shuai Wang, Mao Chen, Wenbo Tang, Yufeng Guo, Yuekai Wen, Lingzhi Yang   +7 more
doaj   +1 more source

Investigation on Saprolitic Laterite Ore Reduction Process using Palm Kernel Shell Charcoal: Kinetics and Phase Transformation

International Journal of Technology, 2022
The performance and kinetic of saprolitic laterite reduction using palm kernel shell charcoal and anthracite were studied. The anthracite coal represents the conventional high-grade carbon content matter, and palm kernel shell charcoal represents ...
Himawan Tri Bayu Murti Petrus, Andreas Diga Pratama Putera, I Wayan Warmada, Fajar Nurjaman, Widi Astuti, Agus Prasetya   +5 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Reduction Kinetics of Vanadium-Titanium Magnetite Sinter When Shale Gas Is Injected into the Blast Furnace

Alloys
Although the composition of hearth gas in a blast furnace is still composed of CO, H2, and N2, after injecting shale gas, which replaces some pulverized coal, the proportion of CO, H2, and N2 in the hearth gas will change with the introduction of H2 ...
Xudong Gao, Jian Chen, Yuelin Qin
doaj   +1 more source

Kinetics of Selective Catalytic Reduction of Nitric Oxide over Pt-Cu-Zsm5 Catalyst

International Islamic University Malaysia Engineering Journal, 2012
Kinetics for the selective catalytic reduction (SCR) of nitric oxide (NO) using i-C4H10 as the reducing agent over Pt-Cu-ZSM5 has been investigated in the temperature range of 200 ?C – 450 oC.
Ismail Mohd Saaid, Abdul Rahman Mohamed and Subhash Bhatia   +1 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Effects of CaO, MgO, Al2O3 and SiO2 on the carbothermic reduction of synthetic FeCr2O4 [PDF]

Journal of Mining and Metallurgy. Section B: Metallurgy, 2015
In order to optimize the current reduction process of chromite, a good knowledge of reduction mechanism involved is required. The basic component in chromite ore is FeCr2O4 with gangue component like MgO and Al2O3.
Wang Y., Wang L., Chou K.C.
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Kinetics of iron reduction upon reduction/oxidation cycles

International Journal of Hydrogen Energy
inglese
Cerciello F., Fabozzi A., Yannakis C., Schmitt S., Narin O., Scherer V., Senneca O.   +6 more
openaire   +1 more source