Results 111 to 120 of about 441,303 (257)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The doubled geometry of nilmanifold reductions

open access: yesJournal of High Energy Physics, 2019
A class of special holonomy spaces arise as nilmanifolds fibred over a line interval and are dual to intersecting brane solutions of string theory. Further dualities relate these to T-folds, exotic branes, essentially doubled spaces and spaces with R ...
N. Chaemjumrus, C.M. Hull
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Robust Reductions

open access: yes, 1997
We continue the study of robust reductions initiated by Gavald`a and Balc'azar. In particular, a 1991 paper of Gavald`a and Balc'azar [GB91] claimed an optimal separation between the power of robust and nondeterministic strong reductions ...
Lane A. Hemaspaandra   +2 more
core  

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Robust Reductions

open access: yes, 2012
We continue the study of robust reductions initiated by Gavald\`{a} and Balc\'{a}zar. In particular, a 1991 paper of Gavald\`{a} and Balc\'{a}zar claimed an optimal separation between the power of robust and nondeterministic strong reductions ...
Cai, Jin-Yi   +2 more
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

On the isomorphism conjecture for 2DFA reductions

open access: yes, 1996
The degree structure of complete sets under 2DFA reductions is investigated. It is shown that, for any class C that is closed under log-lin reductions: All complete sets for the class C under 2DFA reductions are also complete under one-one, length ...
Agrawal, Manindra, Venkatesh, S.
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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