Results 31 to 40 of about 293,359 (293)
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Chiller Fault Diagnosis Based on Automatic Machine Learning
Frontiers in Energy Research, 2021 Intelligent diagnosis is an important means of ensuring the safe and stable operation of chillers driven by big data. To address the problems of input feature redundancy in intelligent diagnosis and reliance on human intervention in the selection of ...
Chongyi Tian +4 more
doaj +1 more source
, 2014 Packet loss is undesirable for real-time multimedia sessions but can occur due to a variety of reasons including unplanned network outages. In unicast transmissions, recovering from such an outage can be difficult depending on the outage ...
Begen, A., Perkins, C.
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
International Journal of Aerospace EngineeringThe continuous advancement of aeronautical engineering technologies, combined with increasingly application demands, has led to the development of aircraft with larger scale and higher value.
An Wang +4 more
doaj +1 more source
REVOLUTIONIZING FEATURE ENGINEERING FOR ROBUST ENSEMBLE MACHINE LEARNING BY HYBRIDIZING MRMR INSIGHT AND CHI2 INDEPENDENCE [PDF]
Proceedings on Engineering SciencesIn the realm of data science, dealing with real-world datasets often presents a formidable challenge, primarily due to the sheer volume of features that significantly lack relevance or may be redundant.
Silpa N +2 more
doaj +1 more source
Cyber Resilience Enabled by Endogenous Safety and Security: Vision, Techniques, and Strategies
中国工程科学, 2023 Cyber resiliency engineering is a technical approach embraced by countries and regions such as the United States and Europe to implement digital transformation and address network security challenges under new circumstances.
Wu Jiangxing +4 more
doaj +1 more source
Software redundancy: what, where, how [PDF]
, 2017 Software systems have become pervasive in everyday life and are the core component of many crucial activities. An inadequate level of reliability may determine the commercial failure of a software product.
Carzaniga, Antonio +2 more
core
A hyper-redundant manipulator [PDF]
, 1994 “Hyper-redundant” manipulators have a very large number of actuatable degrees of freedom. The benefits of hyper-redundant robots include the ability to avoid obstacles, increased robustness with respect to mechanical failure, and the ability to perform ...
Burdick, Joel W., Chirikjian, Gregory S.
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source