Results 31 to 40 of about 865,993 (309)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song +15 more
wiley +1 more source
Common-cause Failures as Major Issue in Safety of Control Systems
Advances in Electrical and Electronic Engineering, 2013 In order to gain an improvement of safety or availability measures of the safety-relevant control system through employment of redundancy a redundant system has to comply with the requirement on independence of redundant parts. If the requirements on the
Juraj Ilavsky +2 more
doaj +1 more source
Applied Sciences, 2020 Due to the high cost of failures of wind turbines, redundancy designs are commonly applied in wind turbines for improving the reliability and availability of systems.
Yao Li, Caichao Zhu, Zi Wang
doaj +1 more source
Maximum flow-based resilience analysis: From component to system. [PDF]
PLoS ONE, 2017 Resilience, the ability to withstand disruptions and recover quickly, must be considered during system design because any disruption of the system may cause considerable loss, including economic and societal.
Chong Jin, Ruiying Li, Rui Kang
doaj +1 more source
Redundant RF system for space application [PDF]
, 1979 An S-band radio frequency subsystem is described including two transmitters, two receivers and two antennas. The subsystem is capable of connecting either transmitter or receiver to either antenna while permitting simultaneous operation of a transmitter ...
Rook, C. W.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Dual redundant core memory systems [PDF]
, 1972 Electronic memory system consisting of series redundant drive switch circuits, triple redundant majority voted memory timing functions, and two data registers to provide functional dual redundancy is described.
Hull, F. E.
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source