Results 71 to 80 of about 707,525 (304)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Reliabilities of redundant electrical generator systems [PDF]
Reliability of redundant electrical generating system configurations for use in SNAP-2 AND SNAP-
Amstadter, B. L.
core +1 more source
Conceptual nonorthogonal gyro configuration for guidance and navigation [PDF]
, 1967 Nonorthogonal sensor configuration using six single-degree-of-freedom inertial reference gyroscopes and a complete data processing and self-contained failure detection-and-isolation mechanism provides redundant capabilities to guidance and navigation ...
Gilmore, J. P.
core +1 more source
Modelling and control of a high redundancy actuator [PDF]
, 2010 The high redundancy actuation concept is a completely new approach to fault tolerance, and it is important to appreciate that it provides a transformation of the characteristics of actuators so that the actuation performance (capability) degrades slowly ...
A.C. Zolotas +14 more
core +2 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Energies, 2018 In recent years, the ultra-high voltage direct current (UHVDC) transmission system has been developed rapidly for its significant long-distance, high-capacity and low-loss properties.
Xing Jiang +3 more
doaj +1 more source
Redundancy of hydraulic flight control actuators [PDF]
The constraint of requiring airplanes to have inherent aerodynamic stability can be removed by using active control systems. The resulting airplane requires control system reliability approaching that of the basic airframe.
Chenoweth, C. C., Ryder, D. R.
core +1 more source
A Topological Separation Condition for Fractal Attractors [PDF]
, 2009 We consider finite systems of contractive homeomorphisms of a complete metric space, which are non-redundant on every level. In general this separation condition is weaker than the strong open set condition and is not equivalent to the weak separation ...
Bedford, T. +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Identification of inverse kinematic parameters in redundant systems: Towards quantification of inter-joint coordination in the human upper extremity. [PDF]
PLoS One, 2022 Khoramshahi M +3 more
europepmc +1 more source