Results 241 to 250 of about 447,630 (329)

The Feasibility of a Chair Yoga Intervention to Improve Mental Health and Wellbeing for Adults With Learning Disabilities: A Pilot Study

open access: yesBritish Journal of Learning Disabilities, EarlyView.
ABSTRACT Background Yoga has been shown to have physical benefits for people with learning disabilities. It is unclear whether the mental health and wellbeing benefits of yoga found in other populations are apparent in people with learning disabilities. This study was a pilot. Method The study comprised three stages.
Dale Metcalfe   +3 more
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown   +2 more
wiley   +1 more source

Variable electrophysiology before and after block of the two delayed rectifier potassium channels in groups of isolated rabbit ventricular cells

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Between‐cell differences in ventricular cardiomyocyte action potential duration (APD) and responses to ion channel block may contribute to pro‐arrhythmic dispersion of myocardial repolarisation. This study quantifies between‐cell physiological and pharmacological variability in the rabbit left ventricle (LV) and uses ...
Rebecca J. Gilchrist   +5 more
wiley   +1 more source

Editorial Perspective: A call for action on imposter participants in child and adolescent mental health research

open access: yesChild and Adolescent Mental Health, EarlyView.
Imposter participants are dishonest participants who fake their identities or exaggerate their experiences to participate in research. This appears to be a rising problem in quantitative and qualitative research as well as lived experience groups for child and adolescent mental health research.
Brian C.F. Ching   +5 more
wiley   +1 more source

Resting energy expenditure in adults with nonalcoholic fatty liver disease and type 2 diabetes mellitus: comparison between measured and predicted values. [PDF]

open access: yesBMC Gastroenterol
Mansour A   +10 more
europepmc   +1 more source

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