Results 181 to 190 of about 194,642 (288)

Fat Oxidation, But Not Subcutaneous Adipose Tissue Lipolysis, Differs Between Males and Females During a Treadmill-Based Heat Tolerance Test. [PDF]

Eur J Sport Sci
Morrissey-Basler MC, Szymanski MR, Filep EM, Langan SP, Ormsbee MJ, Lee EC, Casa DJ.   +6 more
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Applicability of different resting energy expenditure prediction equations to overweight and obese women of childbearing age with fertility problems. [PDF]

Asia Pac J Clin Nutr
Wu X, Xue H, Liang M, Wang Y, Xie Y, Zhai Y, Xu B, Song C, Li X, Lai J, Li Z.   +10 more
europepmc   +1 more source

Variable electrophysiology before and after block of the two delayed rectifier potassium channels in groups of isolated rabbit ventricular cells

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Between‐cell differences in ventricular cardiomyocyte action potential duration (APD) and responses to ion channel block may contribute to pro‐arrhythmic dispersion of myocardial repolarisation. This study quantifies between‐cell physiological and pharmacological variability in the rabbit left ventricle (LV) and uses ...
Rebecca J. Gilchrist, Muhamad Hifzhudin Noor Aziz, Francis L. Burton, Radostin D. Simitev, Rachel C. Myles, Godfrey L. Smith   +5 more
wiley   +1 more source

Predictive equations commonly used in the clinic underestimate resting energy expenditure compared with whole-room indirect calorimetry in colorectal cancer survivors. [PDF]

Am J Clin Nutr
Eklo RR, Alavi DT, Konglevoll DM, Kolle Å, Henriksen HB, Rising R, Blomhoff R, Olsen T.   +7 more
europepmc   +1 more source

Diltiazem N‐oxide, a novel ischaemia‐activated prodrug, prevents ischaemia‐induced ventricular fibrillation without off‐target adverse effects

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ventricular fibrillation (VF) in coronary heart disease accounts for up to 70% of sudden cardiac death. We examined whether diltiazem N‐oxide (DNO) has ischaemia‐selective antiarrhythmic activity. Experimental Approach Randomised and blinded experiments were performed in rat isolated hearts and in anaesthetised rats to ...
Louise M. Hesketh, Gabriel A. Watson, Francesca Mazzacuva, Zoe Hoare, Thomas R. Eykyn, Michael J. Curtis   +5 more
wiley   +1 more source

Urban Biomining of Rare Earth Elements: Current Status and Future Opportunities. [PDF]

ACS Environ Au
Zhang S, Shen Y.
europepmc   +1 more source

Malignancy in Pediatric Hyperfunctioning Thyroid Nodules: A Case Report and Literature Review

Clinical Endocrinology, EarlyView.
ABSTRACT Background Thyroid nodules are rare in children but carry a markedly higher risk of malignancy compared to adults (20%–26% vs. 5%). Hyperfunctioning thyroid nodules are exceptionally uncommon in the pediatric population and are typically benign.
Cristina Clausi, Simona Censi, Jacopo Maria Arnone, Giulia Messina, Ilaria Piva, Fausto Cortese, Loris Bertazza, Susi Barollo, Francesca Galuppini, Marco Zarantonello, Maurizio Iacobone, Gianmaria Pennelli, Caterina Mian   +12 more
wiley   +1 more source

Toward Sustainable Rare Earth Element Production: Key Challenges in Techno-Economic, Life Cycle, and Social Impact Assessment. [PDF]

ACS Sustain Chem Eng
Smerigan A, Shi R, Shi R.
europepmc   +1 more source

Making, Unmaking and Remaking Home: Foster Carers' Home Practices Within Australia's Child Protection System

Child &Family Social Work, EarlyView.
ABSTRACT This paper draws from interviews with 16 foster carers to explore their efforts to make and remake a sense of home for young people in out‐of‐home care. Our findings highlight home as an important idea and a challenge for carers. Home was a deliberate achievement, created through practices that responded to each young person as an individual ...
Sharyn Goudie, Kristin Natalier, Michelle Jones, Kate Seymour   +3 more
wiley   +1 more source