Results 161 to 170 of about 1,854,346 (342)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Testing for reference dependence: an application to the art market [PDF]

open access: yes, 2005
This paper tests for reference dependence, using data from Impressionist and Contemporary Art auctions. We distinguish reference dependence based on rule of thumb learning from reference dependence based on rational learning. Furthermore, we distinguish pure reference dependence from effects due to loss aversion. Thus, we use actual market data to test
Beggs, Alan, Graddy, Kathryn
openaire   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

NEW DIDACTIC MEANS СREATION OF A MEDICAL HIGHER SCHOOL TEACHER AS FACTOR OF HIS PROFESSIONAL-PEDAGOGICAL COMPETENCIES DEVELOPMENT

open access: yesАкушерство, гинекология и репродукция, 2016
The article considers the problem of professional-pedagogical competencies development of the Higher Medical School teacher. It is revealed dependence of improving quality of students’ professional training from the level of the teacher’s psychological ...
O. M. Kolomiets   +2 more
doaj  

Occurrence and Strength of Instantaneous and Intracohort Density‐Dependence in Northeast Atlantic Fish Stocks

open access: yesEcology and Evolution
Biological reference points (BRPs) used in fisheries management do not include density‐dependent (DD) growth, with DD processes only considered in the stock recruitment relationship.
Massimiliano Cardinale   +5 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Estimations of biological motion walking direction are affected by observer and walker genders

open access: yesBMC Psychology
A facing-towards bias is commonly reported when observers are asked to judge the motion directions of others. However, it remains unclear just how accurately observers are able to estimate the motion direction of others and whether the gender of the ...
Qi Sun   +3 more
doaj   +1 more source

Framing social security reform: Behavioral responses to changes in the full retirement age [PDF]

open access: yes
We use a US Social Security reform as a quasi-experiment to provide evidence on framing effects in retirement behavior. The reform increased the full retirement age (FRA) from 65 to 66 in two month increments per year of birth for cohorts born from 1938 ...
David M. Blau, Luc Behaghel
core  

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