Results 271 to 280 of about 1,854,346 (342)

Predictive model of psychological factors influencing university students' intentions and behavior regarding physical exercise-based on machine learning algorithms. [PDF]

Front Psychol
Zhu L, Kong F, Liu T.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Development and validation of a nomogram for predicting frailty among older adults with multimorbidity in the emergency department. [PDF]

Front Med (Lausanne)
Zhang J, Ma M, Xie X, Chu D, Hao J, Zhang W, Deng S, Ouyang P, Guo Z.   +8 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Demand for Commitment Devices: Insights from a Reference Dependence Preferences Model

, 2011
Quang Nguyen
openalex   +1 more source

Mental health profile of culturally and linguistically diverse (CALD) women entering New South Wales public prisons: a retrospective cohort study using real-world data. [PDF]

BMC Psychol
Zeki R, Higgins A, Gill S, Zingirlis P, Kaye S, Chemjong P, Vance A, Howard MVA, Dean K, Bowman J.   +9 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Longitudinal brain atrophy and mortality among people living in homelessness and precarious housing: A brief report of a longitudinal study. [PDF]

PLoS One
Stubbs JL, Jones AA, Gicas KM, Field TS, Heran MKS, Vertinsky AT, Lang DJ, Su W, Thornton AE, MacEwan GW, Leonova O, Rauscher A, Barr AM, Honer WG, Panenka WJ.   +14 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Why Empirical p-Values Are Not Uniform: Reference Samples, Dependence, and PIT Backtesting [PDF]

Jakub Lis
openalex