Results 61 to 70 of about 2,341,324 (289)

Perspectivism and Special Relativity

open access: yesTeorie vědy, 2021
The special theory of relativity holds significant interest for scientific perspectivists. In this paper, I distinguish between two related meanings of “perspectival,” and argue that reference frames are perspectives, provided that perspectival means ...
Mahdi Khalili
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Gauge transformation through an accelerated frame of reference

open access: yes, 2009
The Schr\"{o}dinger equation of a charged particle in a uniform electric field can be specified in either a time-independent or a time-dependent gauge.
Ashish Shukla   +4 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

3D kinematics using dual quaternions: theory and applications in neuroscience

open access: yesFrontiers in Behavioral Neuroscience, 2013
In behavioral neuroscience, many experiments are developed in 1 or 2 spatialdimensions, but when scientists tackle problems in 3-dimensions (3D), theyoften face problems or new challenges. Results obtained for lower dimensionsare not always extendable in
Guillaume eLeclercq   +5 more
doaj   +1 more source

Overall properties of the Gaia DR1 reference frame

open access: yes, 2017
We compare quasar positions of the auxiliary quasar solution with ICRF2 sources using different samples and evaluate the influence on the {\it Gaia} DR1 reference frame owing to the Galactic aberration effect over the J2000.0-J20015.0 period.
Ding, C. -Y.   +3 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Physics within a quantum reference frame

open access: yes, 2011
We investigate the physics of quantum reference frames. Specifically, we study several simple scenarios involving a small number of quantum particles, whereby we promote one of these particles to the role of a quantum observer and ask what is the ...
Angelo, Renato M.   +4 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Degradation of a quantum reference frame

open access: yes, 2006
We investigate the degradation of reference frames, treated as dynamical quantum systems, and quantify their longevity as a resource for performing tasks in quantum information processing. We adopt an operational measure of a reference frame's longevity,
Bartlett, Stephen D.   +3 more
core   +1 more source

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