Results 131 to 140 of about 77,261 (244)

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

Portable Raspberry Pi Platform for Automated Interpretation of Lateral Flow Strip Tests. [PDF]

Sensors (Basel)
Nakou N, Tsikas PK, Kalogianni DP.
europepmc   +1 more source

Engineered Strain in 2D Materials by Direct Growth on Deterministically Patterned Grayscale Topographies

Advanced Science, EarlyView.
ABSTRACT Strain is a proven technique for modifying the bandgap and enhancing carrier mobility in 2D materials. Most current strain engineering techniques rely on the post‐growth transfer of these atomically thin materials from growth substrates to target surfaces, limiting their integration into nanoelectronics.
Berke Erbas, Arindam Bala, Hernan Furci, Anushree Dutta, Naresh Kumar, Renato Zenobi, Giovanni Boero, Andras Kis, Juergen Brugger   +8 more
wiley   +1 more source

PLIN3-triggered lipophagic flux releases FFAs to facilitate CSFV propagation. [PDF]

Virulence
Li B, Zou L, Sun C, Jiang J, Li S, Wang J, He Y, Qin Y, Zeng S, Song Y, Zeng W, Yi L, Fan S, Chen J, Wu K.   +14 more
europepmc   +1 more source

Multi‐Force‐Driven Self‐Recoverable SWIR Mechanoluminescence for Underwater Communication

Advanced Science, EarlyView.
This study represents the first demonstration of self‐recoverable mechanoluminescent (ML) within a single material across diverse mechanical modes, enabled by the synergistic coupling of piezoelectric and triboelectric effects. Through a combinatorial doping approach, the MgNb2O6 crystal exhibits breakthrough short‐wavelength infrared ML performance ...
Jie Sun, Yingqiang Li, Lei Wang, Li Li, Bo Zhao, Yu Wang, Yu Zhang, Xian Zheng, Jiale Zhang, Xinhong Wen, Guodong Zhang, Zhijun Wang, Panlai Li, Hao Suo   +13 more
wiley   +1 more source

Water‐Assisted Exfoliation of HfO2‐Based Membrane for Flexible Robust Ferroelectric Synaptic Transistors

Advanced Science, EarlyView.
A flexible freestanding HfO2‐based ferroelectric membrane is achieved via a water‐assisted exfoliation technique using a Sr4Al2O₇ sacrificial layer. The BaTiO3/Hf0.5Zr0.5O2/BaTiO3 heterostructure maintains robust ferroelectricity and exhibits reliable synaptic plasticity.
Han Zhang, Miao Zeng, Jingxin Chen, Lei Wang, Sai Jiang, Qian Cao, Xuebo Li, Zekun Hou, Chun Shen, Yulin Gan, Ning Fang, Zhaoliang Liao, Ziyao Zhou, Lin Hao   +13 more
wiley   +1 more source

Beyond Global Shannon Entropy: A Channel-Specific Approach to Quantify Polychromia in Melanoma. [PDF]

Cureus
Martínez-Ortega JI, Martinez-Jaramillo B.   +1 more
europepmc   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Ultrasound histogram metrics for subscapularis tendon: Toward standardized musculoskeletal image interpretation. [PDF]

Medicine (Baltimore)
Abdeen R.
europepmc   +1 more source

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

Advanced Science, EarlyView.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang, Wenjing Xu, Yafang Lu, Huaibin Yu, Zhengbao Zha, Xijun Zhang   +5 more
wiley   +1 more source