Results 11 to 20 of about 7,745,372 (343)

Development of next-generation reference interval models to establish reference intervals based on medical data: current status, algorithms and future consideration

Critical reviews in clinical laboratory sciences, 2023
Evidence derived from laboratory medicine plays a pivotal role in the diagnosis, treatment monitoring, and prognosis of various diseases. Reference intervals (RIs) are indispensable tools for assessing test results.
Chaochao Ma, Zheng Yu, Ling Qiu
semanticscholar   +1 more source

Distribution and reference interval establishment of neutral‐to‐lymphocyte ratio (NLR), lymphocyte‐to‐monocyte ratio (LMR), and platelet‐to‐lymphocyte ratio (PLR) in Chinese healthy adults

Journal of clinical laboratory analysis (Print), 2021
Neutral‐to‐lymphocyte ratio (NLR), lymphocyte‐to‐monocyte ratio (LMR), and platelet‐to‐lymphocyte ratio (PLR) are associated with coronavirus disease 2019 (COVID‐19) and many diseases, but there are few data about the reference interval (RI) of NLR, LMR,
Junjun Wang, Fan Zhang, Feng Jiang, Li-Zhen Hu, Jian Chen, Yumin Wang   +5 more
semanticscholar   +1 more source

Serum GFAP – reference interval and preanalytical properties in Danish adults

Clinical Chemistry and Laboratory Medicine, 2022
Objectives Glial fibrillary acidic protein (GFAP) is a promising biomarker that could potentially contribute to diagnosis and prognosis in neurological diseases.
Lea Tybirk, C. H. B. Hviid, C. S. Knudsen, T. Parkner   +3 more
semanticscholar   +1 more source

refineR: A Novel Algorithm for Reference Interval Estimation from Real-World Data

Scientific Reports, 2021
Reference intervals are essential for the interpretation of laboratory test results in medicine. We propose a novel indirect approach to estimate reference intervals from real-world data as an alternative to direct methods, which require samples from ...
T. Ammer, A. Schützenmeister, H. Prokosch, M. Rauh, Christopher M Rank, J. Zierk   +5 more
semanticscholar   +1 more source

RIbench: A Proposed Benchmark for the Standardized Evaluation of Indirect Methods for Reference Interval Estimation.

Clinical Chemistry, 2022
BACKGROUND Indirect methods leverage real-world data for the estimation of reference intervals. These constitute an active field of research, and several methods have been developed recently.
T. Ammer, A. Schützenmeister, H. Prokosch, J. Zierk, Christopher M Rank, M. Rauh   +5 more
semanticscholar   +1 more source

Reference interval transference of common clinical biomarkers

Scandinavian Journal of Clinical and Laboratory Investigation, 2021
Clinical examination has become an important method of disease diagnosis, curative effect evaluation, prognosis judgment and health monitoring, and the biological reference interval is the reference standard to interpret test results and analyses of test
Panyang Xu, Qi Zhou, Jiancheng Xu
semanticscholar   +1 more source

Application of the TML method to big data analytics and reference interval harmonization

Journal of Laboratory Medicine, 2021
Significant variation in reported reference intervals across healthcare centers and networks for many well-standardized laboratory tests continues to exist, negatively impacting patient outcomes by increasing the risk of inappropriate and inconsistent ...
M. K. Bohn, K. Adeli
semanticscholar   +1 more source

Functional reference limits: a case study of serum ferritin

Journal of Laboratory Medicine, 2021
Reference intervals depend on the distribution of results within a reference population and can be influenced by subclinical disease. Functional reference limits present an opportunity to derive clinically relevant reference limits from routinely ...
Sezgin Gorkem, Loh Tze Ping, Markus Corey   +2 more
doaj   +1 more source

Reference Interval Estimation from Mixed Distributions using Truncation Points and the Kolmogorov-Smirnov Distance (kosmic)

Scientific Reports, 2020
Appropriate reference intervals are essential when using laboratory test results to guide medical decisions. Conventional approaches for the establishment of reference intervals rely on large samples from healthy and homogenous reference populations ...
J. Zierk, F. Arzideh, L. Kapsner, H. Prokosch, M. Metzler, M. Rauh   +5 more
semanticscholar   +1 more source

Establishment of reference interval for thyroid-stimulating hormone using electrochemiluminescence assay in a healthy adult population from Fortaleza, Brazil

Archives of Endocrinology and Metabolism, 2020
Objective This study aimed to determine the thyroid-stimulating hormone (TSH) reference interval (RI) and to assess the influence of the use of thyroid ultrasonography (TUS) on reference individual selection from a healthy adult population in Fortaleza,
Maria Helane C Gurgel, Clarisse M. M. Ponte, Rosita Fontes, Ítalo V. Rocha, Lívia A. A. Batista, Tamara C. S. Sousa, Renan M. Montenegro Junior   +6 more
doaj   +1 more source