Results 241 to 250 of about 2,495,085 (292)

Big data and reference intervals

Clinica Chimica Acta, 2022
Although reference intervals (RIs) play an important role in clinical diagnosis, there remain significant differences with respect to race, gender, age and geographic location. Accordingly, the Clinical Laboratory Standards Institute (CLSI) EP28-A3c has recommended that clinical laboratories establish RIs appropriate to their subject population ...
Dan, Yang, Zihan, Su, Min, Zhao
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Reference Intervals in Coagulation Analysis

Hämostaseologie, 2022
AbstractBlood coagulation analysis is characterized by the application of a variety of materials, reagents, and analyzers for the determination of the same parameter, or analyte, by different laboratories worldwide. Accordingly, the application of common reference intervals, that, by definition, would represent a “range of values (of a certain analyte)
Müller, Jens, Büchsel, Martin, Timme, Michael, App, Urban, Miesbach, Wolfgang, Sachs, Ulrich J., Krause, Michael, Scholz, Ute   +7 more
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Reference intervals: an update

Clinica Chimica Acta, 2003
Reference intervals serve as the basis of laboratory testing and aid the physician in differentiating between the healthy and diseased patient. Standard methods for determining the reference interval are to define and obtain a healthy population of at least 120 individuals and use nonparametric estimates of the 95% reference interval.
Paul S, Horn, Amadeo J, Pesce
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Reference intervals: the way forward

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2009
New facts have recently enhanced interest in the topic of reference intervals. In particular, the International Organization for Standardization standard 15189, requesting that ‘biological reference intervals shall be periodically reviewed’, and the directive of the European Union on in vitro diagnostic medical devices asking manufacturers to provide ...
F. Ceriotti, R. Hinzmann, M. Panteghini
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Haemostatic reference intervals in pregnancy

Thrombosis and Haemostasis, 2010
SummaryHaemostatic reference intervals are generally based on samples from non-pregnant women. Thus, they may not be relevant to pregnant women, a problem that may hinder accurate diagnosis and treatment of haemostatic disorders during pregnancy. In this study, we establish gestational age-specific reference intervals for coagulation tests during ...
Szecsi, Pal Bela, Jørgensen, Maja, Klajnbard, Anna, Andersen, Malene R, Colov, Nina Sigyn Palmgren, Stender, Steen   +5 more
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Reference intervals, etc.

2017
Abstract This chapter explores reference intervals, including statistics in medicine, biochemistry reference intervals, haematology reference intervals, drug therapeutic ranges in plasma, and important drug interactions.
Ian B. Wilkinson, Tim Raine, Kate Wiles, Anna Goodhart, Catriona Hall, Harriet O’Neill   +5 more
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Reference Intervals in Neonatal Hematology

Clinics in Perinatology, 2015
The various blood cell counts of neonates must be interpreted in accordance with high-quality reference intervals based on gestational and postnatal age. Using very large sample sizes, we generated neonatal reference intervals for each element of the complete blood count (CBC).
Erick, Henry, Robert D, Christensen
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Time-qualified reference intervals — chronodesms

Experientia, 1978
Methods are presented for qualifying clinical reference intervals, for individuals as well as peer groups, according to circadian and other rhythms, using chronobiologically-defined single samples or time series.
F, Halberg, J K, Lee, W, Nelson
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Reference intervals, etc.

2014
The Gaussian (‘Normal’) distributionDrug therapeutic ranges in plasmaGentamicinSome important drug interactionsHaematology reference intervalsBiochemistry reference intervalsOnce upon a time, in a famous hospital named R— in the middle of England, there lived a crusty old surgeon and a brilliant young house officer.
Murray Longmore, Ian B. Wilkinson, Andrew Baldwin, Elizabeth Wallin   +3 more
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Paediatric reference intervals

Pathology, 2013
Worldwide there appear to be two main approaches to addressing the gap in paediatric biochemistry reference intervals: (1) large scale, government-funded reference interval studies based on recruiting healthy children, and (2) ‘harmonisation’ to achieve common reference intervals (CRI).
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