Results 141 to 150 of about 11,409,850 (299)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Measuring and Assessing Reference Services and Resources: A Guide Version 2008

open access: yes, 2008
Measuring and Assessing Reference Services and Resources: A Guide offers an expansive definition of reference service, assessment planning advice, and measurement tools to assist managers in evaluating reference services and resources.
RUSA/RSS Evaluation of Reference and User Services Committee
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Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Reference Notes (December 2002)

open access: yes, 2002
Table of Contents includes: Virtual Reference Services Part 2: models of virtual reference; Ebooks: What's the Story?; Information Bits: Minitex Webinars are Here to Stay!Minitex Reference Outreach & Instruction. (2002).
Minitex Reference Outreach & Instruction
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Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

GOST 8.315 "GSI. Reference materials of composition and properties of substances and materials. Basic concepts": basic principles of revision

open access: yesСтандартные образцы, 2017
A key point of the revision of GOST 8.315"GSI. Reference materials of composition and properties of substances and materials. Basic concepts" is harmonization with the documents of International Organization for Standardization (ISO) and International ...
E. V. Osintseva
doaj  

Professional Competencies for Reference and User Services Librarians Version 2017

open access: yes, 2017
As the professional organization for reference and user services, the Reference and Users Services Association (RUSA) has developed and updated a model statement of competencies essential for successful reference and user services ...
RUSA Professional Competencies for Reference and User Services Librarians Task Force
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Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Biology Reference Sheets

open access: yes, 2012
This reference sheet, presented by the National Nanotechnology Infrastructure Network provides a valuable list biology reference material for high school students in the life sciences. Definition of terms, diagrams, abbreviations, mathematical notations,

core  

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