Results 51 to 60 of about 11,409,850 (299)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Activity of All-Russian Research Institute of Physical-Technical and Radio-Technical Measurements (VNIIFTRI) in the sphere of physicochemical measurements

open access: yesСтандартные образцы, 2019
This article presents the description, metrological characteristics and application of State primary standards developed at the All-Russian Research Institute of Physicol-Technical and Radio-Technical Measurements (VNIIFTRI).
V. I. Dobrovolskiy   +2 more
doaj   +1 more source

Definition of Reference 2021

open access: yes, 2021
To update the 2008 version and to extend the conception of reference work beyond the ...
Reference Services Section (RSS) Executive Committee
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Battery Mineral Characterization—A Case Study of a Nickel Reference Material

open access: yesMaterials Proceedings
This study documents the geochemical and mineralogical characteristics of three nickel reference materials for the battery minerals industry: ¼ drill cores of typical nickel-rich ores, centimeter-sized chips of run-of-mine ore, and finely ground nickel ...
Lorenza Sardisco   +9 more
doaj   +1 more source

Development of a reference material for the composition of 0.1 m potassium dichromate solution. Certified reference material GSO 10992-2017

open access: yesСтандартные образцы, 2019
This paper describes key stages in the development and investigation of a high-precision certified reference material (CRM) for the composition of potassium dichromate solution.
A. Yu. Shimolin, A. V. Sobina
doaj   +1 more source

Characterization Model for IC Reference Material

open access: yes, 2011
Not all of the measurement data of IC (Integrated Circuit) reference material are valid, so some work would be do to eliminate the null and wrong ones. This paper presents an algorithmic model of the characterization for IC reference material, which can ...
Ting Zhang, Jian Shi
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Synthesis and Characterization of Ultra‐Small Gold Nanoparticles in the Ionic Liquid 1‐Ethyl‐3‐methylimidazolium Dicyanamide, [Emim][DCA]

open access: yesChemistryOpen
We report on gold clusters with around 62 gold atoms and a diameter of 1.15±0.10 nm. Dispersions of the clusters are long‐term stable for two years at ambient conditions.
Jana Hildebrandt   +2 more
doaj   +1 more source

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