Results 81 to 90 of about 1,725,696 (250)
Global distribution of reference materials. Review
The article is a review material and continuation of a series of articles, based on the research work "The study on global trends and the development of the concept of State Service of Reference Materials", initiated by Federal Agency of Technical ...
N. S. Baratova +2 more
doaj
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Controlling the content of preservatives in soft drinks is of paramount important for assessing their quality during production and consumption, as well as for ensuring consumer health. To effectively enhance laboratory capacity in preservatives analysis,
Le Manh Hung +3 more
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Statistical Identification of Outliers in Ore Gold Reference Material to Determine the Optimal Value
The methods of mathematical statistics were used to distinguish outliers, such as the Grubbs test and the Dixon test. These methods have not completely identified outliers for statistical tests of the analytical results for constant gold standard samples.
YANG Li-qin, MU Xin-hua, ZHENG Zhen-yun
doaj
NISTCHO is a Chinese hamster ovary (CHO) cell line expressing the same amino acid sequences as the heavy and light chains of the National Institute of Standards and Technology (NIST) monoclonal antibody [Reference Material (RM) 8671 NISTmAb]. NISTCHO was
Megan H. Cleveland +6 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Preparation and Certification of Reference Materials for Hydrogen and Oxygen Isotopes in Water
Certified reference materials of water for stable hydrogen and oxygen isotopes were developed and have been used for more than 30 years. However, they no longer meet the requirements for newly developed technologies. New reference materials of water have
ZHANG Lin +3 more
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Glucose meters provide a rapid blood glucose status for evidence-based diagnosis, monitoring, and treatment of diabetes mellitus. We aimed to evaluate the commutability of processed blood materials (PBMs) and their use in the performance evaluation of ...
Napaporn Apiratmateekul +3 more
doaj +1 more source

