Results 241 to 250 of about 17,068,399 (395)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Polymer Capsules with Volatile Organic Compounds as Reference Materials for Controlled Emission. [PDF]
Musyanovych A +7 more
europepmc +1 more source
Standard Reference Materials: Boric Acid; Isotopic, and Assay Standard Reference Materials
C. E. Champion +4 more
semanticscholar +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Development of gene-in-plasmid DNA reference materials certified by single-molecule counting. [PDF]
Lee DH +5 more
europepmc +1 more source
The New Reference Material CRM 470 for Standardizafion of Immunoassays for Plasma Proteins
S Baudner, Francesco Dati
openalex +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Determination of Toxic Elements in Botanical Dietary Supplement Ingredient Reference Materials. [PDF]
Fong Sam J, Kuszak AJ, Gray PJ, Wise SA.
europepmc +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source

