We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
How Well Do We Know VPDB-Part 2: Interlaboratory Assessment of Existing δ<sup>13</sup>C<sub>VPDB</sub> Reference Materials. [PDF]
Moossen H +9 more
europepmc +1 more source
Methods for determining permeability of water-bearing materials, with special reference to discharging-well methods, with a section on direct laboratory methods and bibliography on permeability and laminar flow [PDF]
L.K. Wenzel, V.C. Fishel
openalex +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Can Reference Materials Prepared Following CLSI C37-A Be Utilized Without Commutability Assessment? Perspectives Based on Lipid Measurements. [PDF]
Seo JD +10 more
europepmc +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
From Expert Knowledge to Validation Resources: A Case for Using in Silico Approaches to Close the Gap in Available Reference Materials for Common Germline Genetic Tests. [PDF]
Roy S +16 more
europepmc +1 more source

