Results 101 to 110 of about 976,097 (313)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Wandel der Informationsvermittlung in wissenschaftlichen Bibliotheken : Möglichkeiten neuer Produkte und Dienstleistungen [PDF]

open access: yes, 2002
Most Libraries nowadays offer their catalogues or databases online, but do not adapt their reference services to the new environment. The purpose of this masters' thesis is to analyse what has changed in the field of reference work and to describe how ...
Putz, Michaela
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The typical site conception of scientific library entering the structure of LNS RAS

open access: yesБиблиосфера, 2015
A typical site of a scientific library entering the structure of the Library for Natural Sciences of the Russian Academy of Sciences (LNS RAS) is aimed to meet information needs of a certain scientific team - employees of scientific institutions served ...
A. A. Ivanovsky
doaj  

Using Publishers' Web Sites for Reference Collection Development

open access: yesIssues in Science and Technology Librarianship, 2000
Utilizing publishers' web sites can help librarians locate additional science and technology reference materials which fall within budget constraints while meeting the needs of the patrons.
Melissa Holmberg
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Policy-to-practice context for inclusive education in England, with specific reference to moderate learning difficulties (MLD) [PDF]

open access: yes
The research aim was to investigate the current policy-to-practice context for inclusive education in England for children with Moderate Learning Difficulties (MLD).
Madigan, Susan Louise
core  

Training needs assessment of the Copper Engineering group at ADC [PDF]

open access: yes, 2001
Plan BWhile the telecommunications industry rapidly expands, so too have the Engineering Divisions of ADC. As the Engineering Divisions maintain pace with the demands of the telecommunications industry, ADC needs to look at developing training methods to
Wachter, Jeffrey
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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