Results 281 to 290 of about 7,574,742 (332)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Reference points and roughness

Information Sciences, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Babushri Srinivas Kedukodi   +2 more
openaire   +3 more sources

Goals as Reference Points

Cognitive Psychology, 1999
We argue that goals serve as reference points and alter outcomes in a manner consistent with the value function of Prospect Theory (Kahneman & Tversky, 1979; Tversky & Kahneman, 1992). We present new evidence that goals inherit the properties of the value function-not only a reference point, but also loss aversion and diminishing sensitivity.
C, Heath, R P, Larrick, G, Wu
openaire   +2 more sources

The anterior point of reference

The Journal of Prosthetic Dentistry, 1979
Three points in space determine the position of the maxillary cast in an articulator. The dentist is most frequently concerned with selecting the posterior two of the three reference points. In addition, the dentist will, either consciously or unknowingly, select the anterior of these points of reference.
openaire   +2 more sources

Point of Reference

Leonardo, 1993
GEO-SONIC (1988) is an artwork for computer that explores sound, language and geographics. It is a collage of sounds, speech and calligraphy from around the world that leads the participant in associative global dreams and journeys. Sounds sampled by the artists are digitized and played back, juxtaposed with on-screen visual imagery (by use of a track ...
Madelon Hooykaas, Elsa Stansfield
openaire   +1 more source

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