Results 51 to 60 of about 362,427 (261)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Analyzing the Automatic Power Level Control Effect of a Signal Generator in RF Power Sensor Calibration by a Direct Comparison Transfer Method and a Millimeter Wave Application

Sensors
Most calibration laboratories prefer the Direct Comparison Transfer Method (DCTM) for a reliable and accurate calibration of power sensors in the radio frequency (RF) scope.
Erkan Danaci
doaj   +1 more source

Stabilized Radio Frequency Transfer via 100 km Urban Optical Fiber Link Using Passive Compensation Method

IEEE Access, 2019
A point to point stable radio frequency (RF) signal transfer scheme is proposed and experimentally demonstrated via 100 km noisy urban optical fiber link in Beijing area.
Chenxia Liu, Shujin Zhou, Jianming Shang, Zhuoze Zhao, Hao Gao, Xing Chen, Song Yu   +6 more
doaj   +1 more source

Mixer linearisation for software defined radio applications [PDF]

, 2002
The inherent non-linearity of mixers is particularly acute in broadband receiver design for software defined radio (SDR) applications. Here, the receiver frontend ‘sees’ not only the wanted channel, but also a number of nearby signals.
Beach, MA, MacLeod, JR, Nesimoglu, T, Warr, PA   +3 more
core   +2 more sources

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

A Coherent Dual-Band FMCW Photonic Radar Based on a Synchronized FMCW Optoelectronic Oscillator

IEEE Access
This paper proposes and experimentally demonstrates a novel coherent radar architecture based on a synchronized frequency-modulated continuous-wave optoelectronic oscillator.
Youngseok Bae, Minji Hyun, Joonyong Park
doaj   +1 more source

Phase-Modulation-Based Stable Radio Frequency Transmission via 125 km Fiber Optic Link

IEEE Photonics Journal, 2023
This paper proposes a stable radio frequency (RF) transfer scheme based on phase modulation. The passive compensation method is used to compensate the phase variations.
Chenxia Liu, Tianwei Jiang, Hanyue Wang, Mingzheng Lei, Tao Liu, Song Yu   +5 more
doaj   +1 more source

Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective We aimed to validate the Pediatric Arthritis Ultrasound Scoring System (PAUSS) for upper extremity joints in children with juvenile idiopathic arthritis (JIA). Methods Children with JIA were evaluated for elbow, wrist, or finger arthritis by clinical examination (CE) and musculoskeletal ultrasound (MSUS) with images scored according to the ...
Patricia Vega‐Fernandez, Pinar Ozge Avar‐Aydin, Kelly Rogers, Daniel J. Lovell, Jennifer Huggins, Alexei Grom, Hermine I. Brunner, Grant S. Schulert, Sheila T. Angeles‐Han, Mekibib Altaye, Amy Cassedy, Arthur B. Meyers, Tracy V. Ting   +12 more
wiley   +1 more source

Superconducting resonator used as a beam phase detector

Physical Review Special Topics. Accelerators and Beams, 2003
Beam-bunch arrival time has been measured for the first time by operating superconducting cavities, normally part of the linac accelerator array, in a bunch-detecting mode.
S. I. Sharamentov, R. C. Pardo, P. N. Ostroumov, B. E. Clifft, G. P. Zinkann   +4 more
doaj   +1 more source