Results 91 to 100 of about 741,842 (292)

Normalization of activated partial thromboplastin time and diluted Russell’s viper venom time ratios can be safely omitted in the assessment of lupus anticoagulant

Research and Practice in Thrombosis and Haemostasis
Background: Normalization of lupus anticoagulant (LA) ratios is recommended by both the Clinical & Laboratory Standards Institute and the International Society of Thrombosis and Hemostasis to reduce inter-assay and intra-assay variation.
Adrian Kimiaei, Jovan Antovic, Charlotte Gran   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

NORMAN B. BELECKI

, 2020
TENURE AT NBS/NIST: 1970-1999 INDUCTED into NIST Gallery of Distinguished Scientists, Engineers, and Administrators: 2020 Birth: 1939, Rochester, New York EDUCATION: Clarkson University, BS (Physics), 1962 George Washington University, MSE ...
National Institute of Standards and Technology
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Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Comparison of Spirometry Values Measured in Healthy Adults with International Standards: (A Case Study of Esfarayen)

تحقیقات سلامت در جامعه, 2021
Introduction and purpose: One of the most valuable and widely used methods in screening and evaluating respiratory diseases and diagnosing lung disorders is spirometry and comparing its value with standard references.
Siavash EtemadiNezhad, Khadijeh Gheysar Koushki, Jamshid Yazdani Charati, Seyed Ehsan Samaei   +3 more
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The system of secondary reference standards in drug quality control laboratories

Регуляторные исследования и экспертиза лекарственных средств, 2018
Pharmaceutical reference standards systems have been analyzed. The imperfections of a one-level system have been demonstrated. It has been shown that for making a reliable decision on the quality of medicines one needs to use a two-level system, an ...
D. A. Leontiev
doaj  

Quantitative faecal immunochemical tests to guide colorectal cancer pathway referral in primary care. A systematic review, meta-analysis and cost-effectiveness analysis

Health Technology Assessment
Background Faecal immunochemical tests may be better than symptoms alone at identifying which patients who present to primary care with symptoms are at high risk of colorectal cancer and should have a colonoscopy.
Sue Harnan, Aline Navega Biz, Jean Hamilton, Sophie Whyte, Emma Simpson, Shijie Ren, Katy Cooper, Mark Clowes, Muti Abulafi, Alex Ball, Sally C Benton, Richard Booth, Rachel Carten, Stephanie Edgar, Willie Hamilton, Matt Kurien, Louise Merriman, Kevin Monahan, Laura Heathcote, Matt Stevenson   +19 more
doaj   +1 more source

Characterization of Primary Standards for Use in the HPLC Analysis of the Procyanidin Content of Cocoa and Chocolate Containing Products

Molecules, 2009
This report describes the characterization of a series of commercially available procyanidin standards ranging from dimers DP = 2 to decamers DP = 10 for the determination of procyanidins from cocoa and chocolate.
Mark J. Payne, David A. Stuart, Matthew Davey, William J. Hurst, Jan A. Glinski, Bruce Stanley   +5 more
doaj   +1 more source

Minimum Income Standards and Reference Budgets : International and Comparative Policy Perspectives

, 2020
Research into minimum income standards and reference budgets around the world is compared in this illuminating collection from leading academics in the field.

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