Results 141 to 150 of about 655,437 (260)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Six-minute walk distance in healthy subjects: reference standards from a general population sample. [PDF]

Respir Res, 2022
Cazzoletti L, Zanolin ME, Dorelli G, Ferrari P, Dalle Carbonare LG, Crisafulli E, Alemayohu MA, Olivieri M, Verlato G, Ferrari M.   +9 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Standard Reference Materials

, 1986
K L Eckerle, R Mavrodineanu, R A Velapoldi, B Adams, V R Weidner   +4 more
openaire   +2 more sources

Classification of overweight/obesity among Saudi adolescents relative to lifestyle behaviors using the IOTF or WHO reference standards. [PDF]

Front Pediatr
Al-Hazzaa HM, Alhakami A, Alotaibi AM.
europepmc   +1 more source

Physical fitness reference standards for Chinese children and adolescents. [PDF]

Sci Rep, 2021
Zhang F, Bi C, Yin X, Chen Q, Li Y, Liu Y, Zhang T, Li M, Sun Y, Yang X.   +9 more
europepmc   +1 more source

Reference standards.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979
G, Myers, J, Quirk, V, Poplak
openaire   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Designing a set of reference standards for non-targeted analysis of polymer additives extracted from medical devices. [PDF]

J Expo Sci Environ Epidemiol
Yun BH, Herath A, Jin Y, Kim J, Belton K, Rufer E, Rivera Betancourt O.   +6 more
europepmc   +1 more source

Reference standards for flow cytometric estimation of absolute nuclear DNA content in plants. [PDF]

Cytometry A, 2022
Temsch EM, Koutecký P, Urfus T, Šmarda P, Doležel J.   +4 more
europepmc   +1 more source