Reference Standards to Support Quality of Synthetic Peptide Therapeutics. [PDF]
Peptides are an important class of therapeutics. Their quality is evaluated using a series of analytical tests, many of which depend on well-characterized reference standards to determine identity, purity, and strength.
McCarthy D +7 more
europepmc +2 more sources
Clinically Adjudicated Reference Standards for Evaluation of Infectious Diseases Diagnostics. [PDF]
Patel R +5 more
europepmc +2 more sources
Strategies for building reference standards for autoantibodies
Producing robust, certified, traceable reference material for autoantibody testing is a vital element in maintaining the validity of results that are generated in the daily clinical laboratory routine. This is a huge challenge because of the high number
Joanna eSheldon, Alessandra eDellavance
doaj +2 more sources
Differences in Molecular Subtype Reference Standards Impact AI-based Breast Cancer Classification with Dynamic Contrast-enhanced MRI. [PDF]
Background Breast cancer tumors can be identified as different luminal molecular subtypes depending on either immunohistochemical (IHC) staining or St Gallen criteria that includes Ki-67.
Ji Y +5 more
europepmc +2 more sources
Misuse of Pollution Reference Standards: No Safe Level of Air Pollution. [PDF]
The burden of ill health owing to exposure to air pollution is well established and widely accepted (1). Despite this, effective regulation of exposure to air pollution has lagged in many countries.
Marks GB.
europepmc +2 more sources
Physical fitness reference standards for Chinese children and adolescents. [PDF]
To develop age- and sex-specific physical fitness reference standards and express the age- and sex-related differences using standardized effect sizes for Chinese children and adolescents.
Zhang F +9 more
europepmc +2 more sources
Improving reference standards for validation of AI-based radiography. [PDF]
Objective: Demonstrate the importance of combining multiple readers' opinions, in a context-aware manner, when establishing the reference standard for validation of artificial intelligence (AI) applications for, e.g. chest radiographs.
Duggan GE +4 more
europepmc +2 more sources
Reference standards for flow cytometric estimation of absolute nuclear DNA content in plants. [PDF]
The estimation of nuclear DNA content has been by far the most popular application of flow cytometry in plants. Because flow cytometry measures relative fluorescence intensities of nuclei stained by a DNA fluorochrome, ploidy determination, and ...
Temsch EM +4 more
europepmc +2 more sources
Reference Standards for Cardiorespiratory Fitness by Cardiovascular Disease Category and Testing Modality: Data From FRIEND. [PDF]
Background The importance of cardiorespiratory fitness for stratifying risk and guiding clinical decisions in patients with cardiovascular disease is well‐established.
Peterman JE +7 more
europepmc +2 more sources
The Science Behind Nefertiti's Beauty: A Plastic Surgeon's Analysis
Introduction The famous stucco limestone coated “Bust of Nefertiti” housed in the Neues Museum, Germany dated 1,345 BC is an icon of beauty. Sculpted around three millennia ago by Thutmose, the bust still emits a charm that leaves its audience spellbound.
Neha Chauhan
doaj +1 more source

