Results 61 to 70 of about 11,084,989 (407)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Flux calibration of medium-resolution spectra from 300 nm to 2500 nm: Model reference spectra and telluric correction [PDF]

open access: yes, 2014
While the near-infrared wavelength regime is becoming more and more important for astrophysics there is a marked lack of spectrophotometric standard star data that would allow the flux calibration of such data. Furthermore, flux calibrating medium- to high-resolution \'echelle spectroscopy data is challenging even in the optical wavelength range ...
arxiv   +1 more source

High-accuracy reference standards for two-photon absorption in the 680-1050 nm wavelength range.

open access: yesOptics Express, 2016
Degenerate two-photon absorption (2PA) of a series of organic fluorophores is measured using femtosecond fluorescence excitation method in the wavelength range, λ2PA = 680-1050 nm, and ~100 MHz pulse repetition rate. The function of relative 2PA spectral
S. de Reguardati   +4 more
semanticscholar   +1 more source

Laser interferometry method for absolute measurement of the acceleration of gravity [PDF]

open access: yes, 1971
Gravimeter permits more accurate and precise absolute measurement of g without reference to Potsdam values as absolute standards. Device is basically Michelson laser beam interferometer in which one arm is mass fitted with corner cube ...
Hudson, O. K.
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Normative data for middle-aged Brazilians in the Mattis Dementia Rating Scale

open access: yesDementia & Neuropsychologia, 2020
. Despite the advances in the diagnosis of dementia, neuropsychological assessment remains an important tool. The Mattis Dementia Rating Scale (DRS) was designed to evaluate people with suspected dementia and allows for the analysis of different ...
Guilherme Almeida Carvalho   +1 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Sensor systems: a hierarchical approach [PDF]

open access: yes, 2011
The concept of a reference model has been well known in the communications industry for many years. This has provided clearly defined layers and interface standards which allow different organisations and across the industry to develop products ...
Bremner, Duncan
core  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Systematic Review of the Diagnostic Accuracy of Haptoglobin, Serum Amyloid A, and Fibrinogen versus Clinical Reference Standards for the Diagnosis of Bovine Respiratory Disease

open access: yesJournal of Veterinary Internal Medicine, 2016
Background Bovine respiratory disease (BRD) is a worldwide animal health concern especially in feedlot, dairy, and veal calves. One of the greatest challenges is the absence of a gold standard for achieving an accurate antemortem diagnosis. Various blood
A. Abdallah   +5 more
semanticscholar   +1 more source

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