Results 81 to 90 of about 2,834,850 (218)
Orphanet Journal of Rare DiseasesBackground Calpainopathies, including limb-girdle muscular dystrophy recessive type 1 (LGMD R1) and the rare dominant type 4 (LGMD D4), are genetic neuromuscular disorders caused by pathogenic variants in the CAPN3 gene, which encodes calpain-3, a muscle-
Gianmarco Severa +16 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Transformation of coordinate systems: software, limits and potentialities
Forest@, 2004 The use of different reference systems has involved the need of suitable methodologies for the transformation between coordinate systems. Nowadays such a need is done strong because of the diffusion of Geographical Information Systems (GIS) and by the ...
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Introductory lecture: when the density of the noninteracting reference system is not the density of the physical system in density functional theory. [PDF]
Faraday Discuss, 2020 Jin Y, Su NQ, Chen Z, Yang W.
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
BMC Public HealthBackground The consequences of trace element exposure on cognitive function in elderly adults have been recognized as primarily attributed to the inflammatory response. It is noteworthy that diet can either exacerbate or reduce the inflammatory response.
Chunlan Tang, Min Shen, Hang Hong
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Blockchain Reference System Architecture Description for the ISA95 Compliant Traditional and Smart Manufacturing Systems. [PDF]
Sensors (Basel), 2020 Yalcinkaya E, Maffei A, Onori M.
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Orphanet Journal of Rare DiseasesBackground Myasthenia gravis (MG) is a rare autoimmune disorder. Several new treatment concepts have emerged in recent years, but access to these treatments varies due to differing national reimbursement regulations, leading to disparities across Europe.
Abderhmane Slioui +21 more
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Siriraj's Oxygen System : Document for Reference and Maintenance
Siriraj Medical Journal, 2020 This cross-sectional study was done during January to March 1999 by anesthesiologists, engineers and technicians to investigate the whole oxygen system in Siriraj hospital.
Preecha Soontranan, Pradit Somprakit
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