Results 121 to 130 of about 33,502,480 (330)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time and Length Scales of the Martian Atmospheric Turbulence as Observed by the InSight Lander
We provide a statistical analysis of the Martian near‐surface atmospheric turbulence based on in situ wind observations from NASA's InSight lander. We focus on the variations in length and time scales of the Martian atmospheric turbulence caused by the ...
Orkun Temel, Ozgur Karatekin
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Proteomics Analysis of Duck Lung Tissues in Response to Highly Pathogenic Avian Influenza Virus
Domestic ducks (Anas platyrhynchos domesticus) are resistant to most of the highly pathogenic avian influenza virus (HPAIV) infections. In this study, we characterized the lung proteome and phosphoproteome of ducks infected with the HPAI H5N1 virus (A ...
Periyasamy Vijayakumar +7 more
doaj +1 more source
External Disturbances Rejection for Vector Field Sensors in Attitude and Heading Reference Systems. [PDF]
Wang Y, Li Z, Li X.
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The outer solar system beyond Saturn remains unexplored by dedicated orbital missions. With a launch window opening in 2029, the Uranus Orbiter and Probe (UOP) mission has been prioritized as a NASA Flagship mission for the next decade (2023–2032) to ...
Valerio Filice +6 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Adaptive Control for Singularly Perturbed Systems
Singularly perturbed systems are a class of mathematical systems that are not well approximated by their limits and can be used to model plants with multiple fast and slow states.
Kameron Eves, John Valasek
semanticscholar +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

