Results 181 to 190 of about 33,502,480 (330)

European Reference Networks - a flagship activity of the EU in the field of rare and complex diseases: from 2017 to 2025. [PDF]

Orphanet J Rare Dis
Graessner H, Ripp S, Pereira AM, Schaefer F, Mathijssen I, Blay JY, Mulders PFA, Evangelista T, Ligtenberg MJL, Wilde AAM, Ladenstein R, Lohse AW, Mosca M, Swart JF, Hernández F, Fenaux P, Dollfus H, Verloes A, Wagner T, Bodemer C, Wijnen R, Scarpa M, Jondeau G, Tumienė B, Gallina S, Arzimanoglou A, Sangiorgi L.   +26 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Novel Robotic Test Rig for Camshaft Geometry Measurement with a Collaborative Robot. [PDF]

Sensors (Basel)
Sękala A, Królicki J, Blaszczyk T, Ociepka P, Foit K, Kost G, Kaźmierczak M, Gołda G, Jamrozik W.   +8 more
europepmc   +1 more source

Effective Adaptive Kalman Filter for MEMS-IMU/Magnetometers Integrated Attitude and Heading Reference Systems

Journal of navigation, 2012
Wei Li, Jinling Wang
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Computational chemistry methods based on MNDO and tools for improving their accuracy. [PDF]

J Mol Model
Stewart JJP.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

The IERS Conventions (2010): reference systems and new models

Proceedings of the International Astronomical Union, 2012
B. Luzum, G. Petit
semanticscholar   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Researcher population pyramids: Tracking demographic and gender trajectories across countries. [PDF]

PNAS Nexus
Nakajima K, Mizuno T.
europepmc   +1 more source