Results 231 to 240 of about 33,502,480 (330)

Investigating perceptual discrimination thresholds for attributes of whole-body vibration. [PDF]

Sci Rep
Kullukcu B, Krautwurm J, Merchel S, Rosenkranz R, Altinsoy E.   +4 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

How Is Colorectal Cancer Care Impacted by Global Crisis in Contrasting Healthcare Systems?-A Descriptive Study From Scotland and Switzerland During the COVID-19 Pandemic. [PDF]

World J Surg
Wiesler B, Worni M, Studer P, Gass JM, Metzger J, Hartel M, Nebiker C, Rosenberg R, Galli R, Eisner L, Andreou C, Zingg U, Stimpfle D, Viehl CT, Müller A, Müller B, Denhaerynck K, Hall P, Gallagher C, Karunaratne P, Lilley C, Zuber M, Paterson H, von Strauss Und Torney M.   +23 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

An integrated SMC-NADRC robust control approach for electric power steering systems considering nonlinear friction and parametric uncertainties. [PDF]

PLoS One
Nguyen TA, Nguyen DN.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Perceptions of public and private health services in Poland: findings from a 2025 nationwide survey. [PDF]

BMC Health Serv Res
Olearczyk A, Sękowski K, Jankowski M, Kamińska A, Winciunas P, Grudziąż-Sękowska J.   +5 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Correction: Integrated assessment of greenhouse gas emissions in extensive livestock farming systems. [PDF]

Sci Rep
Horrillo A, Gaspar P, Rodríguez-Ledesma A, Escribano M.   +3 more
europepmc   +1 more source