Results 181 to 190 of about 2,339,293 (309)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

An update on hematologic, biochemical and urinary reference values for Iriomote cats. [PDF]

J Vet Med Sci
Sim JJ, Uchimura Y, Nakanishi N, Izawa M, Takahashi M, Endo Y.   +5 more
europepmc   +1 more source

Reference values of hematological and blood biochemical parameters for the Noma horse

, 2019
Tetsushi Ono, Yutaka Yamada, Akihisa Hata, Takako SHIMOKAWA MIYAMA, Ken-ichi SHIBANO, Eri Iwata, Emi OHZAWA, Hitoshi KITAGAWA   +7 more
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Reference values of spherical equivalent for predicting the onset and progression of myopia among children and adolescents in China. [PDF]

Br J Ophthalmol
Qin R, Liu Y, Li H, Xiong Y, Gu F, Shi W, Li T, Xu H, Luo H, Guo X, Liu J.   +10 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Application of Gas Chromatographic Retention Indices to GC and GC-MS Identification with Variable Limits for Deviations Between Their Experimental and Reference Values. [PDF]

Molecules
Zenkevich IG.
europepmc   +1 more source

Reference values for vastus lateralis fiber type proportions and fiber size

, 2013
Harry R. Gosker, Annemie M.W.J. Schols
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Phrenic Nerve Conduction Reference Values in Healthy Adults: An Exploratory Cross-Sectional Study in a Mexican Population. [PDF]

Clin Pract
González-López FJ, Hernández-Cervantes J, Ramírez-Ochoa S, Cervantes-Guevara G, Cervantes-Cardona GA, Hernández-Mora FJ, Vicente-Hernández B, González-Ojeda A, Fuentes-Orozco C, Vázquez-Beltrán JC, Cervantes-Pérez E.   +10 more
europepmc   +1 more source