Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Editorial Note: Research on quantitative evaluation of digital economy policy in China based on the PMC index model. [PDF]
PLOS One Editors.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
RETRACTION: "Image Segmentation of Retinal Blood Vessels Based on Dual-Attention Multiscale Feature Fusion". [PDF]
Methods In Medicine CAM.
europepmc +1 more source
Reference, Real Referants and Discourse Referents
The direct reference theory encounters problems in face of some semantic issues, including reference to non-existents and the substitutivity of co-referent proper names in propositional attitude sentences. That is because the only thing which constitutes the meaning of an expression in this theory is the referent associated with that expression.
openaire +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
La evaluación de la situación nutricional de los niños, depende en gran medida de las curvas de crecimiento utilizadas. El objetivo de esta investigación es comparar las prevalencias de sobrepeso y obesidad estimadas con tres referencias internacionales ...
Gisel Padula, Susana A Salceda
doaj
Reference quality of OpenEvidence across five medical specialties. [PDF]
Lotan T +7 more
europepmc +1 more source
References of references in Robotics. References of references in kinematics and dynamics.
openaire +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source

