Results 71 to 80 of about 1,637,542 (298)

Advanced Transport Operating System (ATOPS) control display unit software description [PDF]

The software created for the Control Display Units (CDUs), used for the Advanced Transport Operating Systems (ATOPS) project, on the Transport Systems Research Vehicle (TSRV) is described.
Debure, Kelly R., Heaphy, William J., Parks, Mark A., Slominski, Christopher J.   +3 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Software Engineering Laboratory (SEL) relationships, models, and management rules [PDF]

Over 50 individual Software Engineering Laboratory (SEL) research results, extracted from a review of published SEL documentation, that can be applied directly to managing software development projects are captured.
Decker, William, Hendrick, Robert, Valett, Jon D.   +2 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Personal reference management software—how to evaluate it? [PDF]

Health Libraries Review, 1991
The background to the development of personal reference management software is outlined and the difference between the two basic types—database management software and text retrieval software—is explained. In conclusion a checklist for evaluating personal reference management software is given.
openaire   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

A Decision Frameworkon Small and Medium Enterprises to Adopt Cloud Software as a Service

MATEC Web of Conferences, 2016
Software as a service (SaaS)is the future trend in software services. However, only a few successful SaaS providerscurrently exist. This study investigated how Taiwanese small and medium enterprises (SMEs) can utilize SaaS, giveSaaSprovidersbusiness ...
Lu Hsi-Peng, Liu Yao-Yuan
doaj   +1 more source

Towards a Reference Framework for Software Product Management

14th IEEE International Requirements Engineering Conference (RE'06), 2006
In the last decade, software product management has received much practical attention, though research in this area is still scattered. In this paper, we present a reference framework for software product management, in which the key process areas, namely portfolio management, product roadmapping, release planning and requirements management, are ...
Weerd, I. van de, Brinkkemper, S., Nieuwenhuis, R., Versendaal, J.M., Bijlsma, L.   +4 more
openaire   +3 more sources

DRIVER Technology Watch Report [PDF]

, 2008
This report is part of the Discovery Workpackage (WP4) and is the third report out of four deliverables. The objective of this report is to give an overview of the latest technical developments in the world of digital repositories, digital libraries and ...
Hochstenbach, Patrick, Karstens Elbaek, Mikael, Russell, Rosemary, Schmelz Pedersen, Gerd, Van Godtsenhoven, Karen, Vanderfeesten, Maurice   +5 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source