Results 281 to 290 of about 1,304,544 (358)

Design and early evaluation of a social care network's impact on health care costs. [PDF]

Health Aff Sch
Galper K, Miguel C, LeJeune K, Rung JM, Eddy B, Kale A, Schano M, Brignone E.   +7 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Assessing the Implementation of Electronic Kidney Transplant Referral and Communication Programs. [PDF]

Kidney Int Rep
Blythe E, McPherson L, Pastan S, Patzer RE, Urbanski M.   +4 more
europepmc   +1 more source

The Widyatama Campus Environmental Planning Study refers to the Law of the Republic of Indonesia Number 26 of 2007 About Spatial Planning for Flood Discharge

Bambang Widyanto, Asep Setiawan, Yanyan Agustian   +2 more
openalex   +2 more sources

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

The Six Delays Model: expanding the three delays model with evidence from Madagascar for maternal referrals in LMICs. [PDF]

BMJ Glob Health
Franke MA, Iata Pasteur G.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Disclaimers and Referral Patterns for Medical Advice Across Urgency Levels: Large Language Model Evaluation Study.

J Med Internet Res
Reis F, Agha-Mir-Salim L, Hickstein R, Reis M, Piper SK, Balzer F, Boie SD.   +6 more
europepmc   +1 more source

A Picture Is Worth a Thousand Words: Improving Efficiency in Teledermatology Triage of Skin Cancer Referrals. [PDF]

Cureus
O'Hara N, Ajmal S.
europepmc   +1 more source