Results 231 to 240 of about 136,865 (342)

Altering physician referral practices is challenging, but not impossible: spine assessment clinic quality improvement study. [PDF]

BMJ Open Qual
Varga A, Slomp F, Ritchie V, Slater-Maclean L, Thiessen E, Hockley A.   +5 more
europepmc   +1 more source

A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness

Advanced Science, EarlyView.
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger, Paolo Cardone, Charlotte Martial, Yonatan Sanz Perl, Iván Mindlin, Jacobo D Sitt, Leor Roseman, Robin Carhart‐Harris, David Nutt, Pablo Mallaroni, Natasha Mason, Johannes G Ramaekers, Vincent Bonhomme, Steven Laureys, Gustavo Deco, Olivia Gosseries, Pablo Núñez, Jitka Annen   +17 more
wiley   +1 more source

Gender-Specific Effects of Delay in Cardiology Consultation Following Primary Care Physician Referral in Atrial Fibrillation Patients: Impact on One-Year Outcomes

Óscar Otero García, Pablo de la Fuente-López, Sergio Cinza‐Sanjurjo, Alberto Cordero, Pilar Mazón‐Ramos, Daniel Rey‐Aldana, Inés Gómez‐Otero, Manuel Portela‐Romero, David García‐Vega, José Ramón González‐Juanatey   +9 more
openalex   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Time intervals in the pathway to diagnosis and treatment of patients with breast and gynecological cancer. [PDF]

Front Med (Lausanne)
Galindo BS, Sotos JR, González ÁL, Díaz MC, Martínez CMS, Hidalgo JL.   +5 more
europepmc   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source

Tele-ophthalmology-enabled and artificial intelligence-ready referral pathway for community optometry referrals of retinal disease: HERMES cluster randomised trial with a diagnostic accuracy study.

Health Technol Assess
Sharma A, Hussain R, Learoyd AE, Aristidou A, Soomro T, Blandford A, Lawrenson JG, Grimaldi G, Douiri A, Kernohan A, Robinson T, Moradi N, Dinah C, Minos E, Sim D, Aslam T, Manna A, Denniston AK, Patel PJ, Keane PA, Bunce C, Vale L, Balaskas K.   +22 more
europepmc   +1 more source

Assessing the Consultation Pattern from Emergency Room Physicians to General Surgery Subspecialties: Identifying the Most Frequently Consulted Subspecialty. [PDF]

Healthcare (Basel)
Al Babtain IT, Alwabel WK, Alhoumaily BA, Alqahtani NA, Almasari RM, Tatwani HT.   +5 more
europepmc   +1 more source