Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Monitoring the Microwave Synthesis of d<sup>0</sup>-Free Disordered Rocksalt Cathodes Using In Situ Infrared Pyrometry. [PDF]
Lawrence EA +8 more
europepmc +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Lattice symmetry relaxation as a cause for anisotropic line broadening and peak shift in powder diffraction. [PDF]
Gregorkiewitz M, Boschetti A.
europepmc +1 more source
An Efficient Method Based on Framelets for Solving Fractional Volterra Integral Equations. [PDF]
Mohammad M, Trounev A, Cattani C.
europepmc +1 more source
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
<i>pyDiSCaMB</i>: enabling the use of multipolar scattering factors in <i>Phenix</i>. [PDF]
Femoen VJ +12 more
europepmc +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Exploring the structural, magnetic, and optical properties of multifunctional Ni<sub>0.4</sub>Mn<sub>0.6</sub>Cr<sub>2</sub>O<sub>4</sub> spinel chromite toward optoelectronic innovation. [PDF]
Hajji ABA +4 more
europepmc +1 more source

