Results 91 to 100 of about 523,498 (290)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2018 Introduction: Manual handling tasks are considered to be the main causes of occupational back pains. Therefore, the assessment of manual handling tasks for the prevention of work musculoskeletal disorders (WMSDs) sounds necessary.
Jafar Akbari +3 more
doaj
Process optimization for the removal of environmental contaminants from fish oils
Oléagineux, Corps gras, Lipides, 2010 Fish oils are rich in nutritionally valuable omega-3 components, mainly eicosapentaenoic (EPA) and docosahexaenoic (DHA) fatty acids. Unfortunately, they could also be contaminated with a series of toxic pollutants like PCDD/Fs and PCBs.
Maes Jeroen +5 more
doaj +1 more source
Refining the stress gradient hypothesis in a microbial community
Proceedings of the National Academy of Sciences of the United States of America, 2019 Microbial species aren’t often found alone, but rather in complex communities containing dozens to hundreds of other species. These species affect one another in many ways.
Sarah P. Hammarlund, W. Harcombe
semanticscholar +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
, 2020 As a technical term in Computer Science, “refinement” is understood as a relation between systems (programs, channels.. ) that, in its most austere form, is simply preservation of properties. © Springer Nature Switzerland AG 2020.
Alvim, M.S. +5 more
openaire +3 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
The effect of refining process on the physicochemical properties and micronutrients of rapeseed oils
PLoS ONE, 2019 Information on the physicochemical variability in rapeseed oil from different varieties during each refining process is lacking. Our purpose was to investigate the physicochemical properties, micronutrients and oxidative stability of the oil extracted ...
Ying Wu +6 more
semanticscholar +1 more source