Results 151 to 160 of about 562,291 (311)

Response to "Refining the Predictive Role of T2-Weighted Imaging Features in Breast Cancer: A Hypothesis Linking Tumor Characteristics to Extreme Chemoresistance". [PDF]

Korean J Radiol
Park VY, Youn I.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Preparation of γ-TiAl Alloys via Self-Propagating Aluminothermic Reduction-Slag Washing Refining Coupled with Vacuum Arc Remelting. [PDF]

Materials (Basel)
Jiang H, Zhang TA, Dou ZH.
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Refining the Predictive Role of T2-Weighted Imaging Features in Breast Cancer: A Hypothesis Linking Tumor Characteristics to Extreme Chemoresistance. [PDF]

Korean J Radiol
Cao J, Tan Y, Zhang L, Gu C, Yang H, Zhang L.   +5 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Techno-Economic Analysis of Lignin-Containing Micro- and Nano-Fibrillated Cellulose for Lightweight Linerboard Packaging

BioResources
A key challenge for the paper industry in adopting nanocellulose materials is finding the right balance between production costs and the benefits for specific paper grades, given the industry’s variety of products and processes.
Heather Starkey, Maria Gonzalez, Hasan Jameel, Lokendra Pal   +3 more
doaj  

Selective Copper Removal from an Fe-P-Cu Alloy Recovered by Pyrometallurgical Reduction of Spent LiFePO₄ Batteries via Sulfidation-Slag Refining. [PDF]

Materials (Basel)
Yoon JS, Im AJ, Wang JP.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Beyond recognition: Refining the assessment of public knowledge and risk perception in dementia prevention. [PDF]

J Prev Alzheimers Dis
Xie Z, Su J, Liao T.
europepmc   +1 more source