Results 61 to 70 of about 216,362 (278)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A metaobject architecture for fault-tolerant distributed systems : the FRIENDS approach [PDF]

open access: yes, 1998
The FRIENDS system developed at LAAS-CNRS is a metalevel architecture providing libraries of metaobjects for fault tolerance, secure communication, and group-based distributed applications.
Fabre, Jean-Charles, Pérennou, Tanguy
core   +2 more sources

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

New Equations for Neutral Terms: A Sound and Complete Decision Procedure, Formalized [PDF]

open access: yes, 2013
The definitional equality of an intensional type theory is its test of type compatibility. Today's systems rely on ordinary evaluation semantics to compare expressions in types, frustrating users with type errors arising when evaluation fails to identify
Allais, Guillaume   +2 more
core   +2 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Distance learning for training business game tutors

open access: yesProduction
This work is the result of research that proposes the incorporation of Distance Learning into a Business Game as a strategy to enhance tutor training, considering entrepreneurship difficulties faced by public school teachers. Part of the problem could be
Mariana de Toledo Marinho   +3 more
doaj   +1 more source

On the Expressiveness of Intensional Communication [PDF]

open access: yes, 2014
The expressiveness of communication primitives has been explored in a common framework based on the pi-calculus by considering four features: synchronism (asynchronous vs synchronous), arity (monadic vs polyadic data), communication medium (shared ...
Given-Wilson, Thomas
core   +6 more sources

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez   +12 more
wiley   +1 more source

Using the Internet of Things to Teach Good Software Engineering Practice to High School Students [PDF]

open access: yes, 2019
This paper describes a course to introduce high school students to software engineering in practice using the Internet Of Things (IoT). IoT devices allow students to get quick, visible results without watering down technical aspects of programming ...
Julien, Christine
core   +1 more source

Daratumumab Treatment for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): A Case Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated neuropathy featuring progressive weakness, sensory deficits, and areflexia. While corticosteroids, intravenous immunoglobulin, and plasmapheresis are effective first‐line immunotherapies, a subset of patients remains treatment‐refractory.
Xueyu Zhang   +8 more
wiley   +1 more source

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