Results 131 to 140 of about 36,597 (305)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Near-Infrared Dual Greenhouse Gas Sensor Based on Hollow-Core Photonic Crystal Fiber for Gas-Cell In-Situ Applications

Sensors
A greenhouse gas sensor has been developed to simultaneously detect multiple gas species within a hollow-core photonic bandgap fiber (HC-PBF) structure entirely composed of fibers.
Jianing Wang, Bingqiang Li, Weiping Wu, Guanyu Lin   +3 more
doaj   +1 more source

Core mode scatterer and fibre end-face mirror incorporated reflective long-period grating sensors

, 2010
A long-period grating (LPG) sensor working in reflection mode is presented for refractive-index sensing applications. The sensor consists of an LPG, a bubble-like core mode scatterer, and a fibre end-face mirror. The light coupled by the LPG is reflected
He, Sailing,, Gu, B., Jiang, M., Wang, Y. C., Zhang, A. P.   +4 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Robust strain sensor based on multimode interference in single-mode–multimode–single-mode fiber structure

, 2018
Single-mode–multimode–single-mode (SMS) structure is demonstrated as a strain sensor. The device is fabricated by splicing a section of multimode optical fiber (MMF) in between single-mode fibers (SMFs).
Harun, Sulaiman Wadi, Razak, Hashim Abdul, Jusoh, Zulzilawati, Azmi, N.M., Yusof, Nur Hotimah   +4 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Broadband High Optical Transparent Intelligent Metasurface for Adaptive Electromagnetic Wave Manipulation

Research
Intelligent metasurfaces have garnered widespread attention owing to their properties of sensing electromagnetic (EM) environments and multifunctional adaptive EM wave manipulation.
Chao Xia, Zhengang Lu, Yilei Zhang, Jiubin Tan   +3 more
doaj   +1 more source

Distributed state estimation for discrete-time sensor networks with randomly varying nonlinearities and missing measurements

, 2011
Copyright [2011] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Liu, X, Liang, J, Wang, Z, null Zidong Wang, null Xiaohui Liu, null Jinling Liang   +5 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Design and fabrication of dual mode pyroelectric sensor: high sensitive energymeter for Nd:YAG laser and detector for chopped He-Ne laser

, 2008
Pyroelectric sensor using TGS has been designed and fabricated which can be operated in laser energy meter mode as well as pyroelectric detector mode. The amplifying circuit configuration has very good signal to noise ratio, very high input impedance and
Satapathy, S., Gupta, P. K., Varma, K. B. R., Dubey, V. K., Soni, Puja   +4 more
core   +1 more source